ID   BAMA_KLEP3              Reviewed;         809 AA.
AC   B5Y1J4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE   Flags: Precursor;
GN   Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN   OrderedLocusNames=KPK_4543;
OS   Klebsiella pneumoniae (strain 342).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=507522;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=342;
RX   PubMed=18654632; DOI=10.1371/journal.pgen.1000141;
RA   Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H.,
RA   Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y.,
RA   Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W.,
RA   Methe B.A.;
RT   "Complete genome sequence of the N2-fixing broad host range endophyte
RT   Klebsiella pneumoniae 342 and virulence predictions verified in mice.";
RL   PLoS Genet. 4:E1000141-E1000141(2008).
CC   -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC       involved in assembly and insertion of beta-barrel proteins into the
CC       outer membrane. Constitutes, with BamD, the core component of the
CC       assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC       membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC       {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
CC   -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
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DR   EMBL; CP000964; ACI09166.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5Y1J4; -.
DR   SMR; B5Y1J4; -.
DR   EnsemblBacteria; ACI09166; ACI09166; KPK_4543.
DR   KEGG; kpe:KPK_4543; -.
DR   HOGENOM; CLU_007664_1_0_6; -.
DR   OMA; IFMPAFG; -.
DR   OrthoDB; 258122at2; -.
DR   Proteomes; UP000001734; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01430; OM_assembly_BamA; 1.
DR   InterPro; IPR000184; Bac_surfAg_D15.
DR   InterPro; IPR010827; BamA/TamA_POTRA.
DR   InterPro; IPR039910; D15-like.
DR   InterPro; IPR023707; OM_assembly_BamA.
DR   InterPro; IPR034746; POTRA.
DR   PANTHER; PTHR12815; PTHR12815; 1.
DR   PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR   Pfam; PF01103; Omp85; 1.
DR   Pfam; PF07244; POTRA; 4.
DR   PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR   TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR   PROSITE; PS51779; POTRA; 5.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Repeat; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT   CHAIN           21..809
FT                   /note="Outer membrane protein assembly factor BamA"
FT                   /id="PRO_1000145780"
FT   DOMAIN          24..91
FT                   /note="POTRA 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          92..172
FT                   /note="POTRA 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          175..263
FT                   /note="POTRA 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          266..344
FT                   /note="POTRA 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          347..421
FT                   /note="POTRA 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ   SEQUENCE   809 AA;  89908 MW;  86A0EF05CAE08010 CRC64;
     MAMKKLLIAS LLFSSATVYG AEGFVVKDIH FEGLQRVAVG AALLSMPVRP GDTVTDDDIS
     NTIRALFATG NFEDVRVLRD GDTLLVQVKE RPTIASITFS GNKSVKDDML KQNLEASGVR
     VGESLDRTTI ADIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFQ EGVSAKIQQI
     NIVGNHAFST DELISHFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSYY LDRGYARFNI
     DSTQVSLTPD KKGIYITVNI TEGDQYKISG VQVTGDLAGH SAEIEALTKV EPGELYNGAK
     VTKMENDIKK LLGRYGYAYP RVQSQPEIND SDKTVKLHVN VDAGNRYYVR KIRFEGNDTS
     KDAVLRREMR QMEGAWLGSD LVDQGKDRLN RLGFFETVDT DTQRVPGSPD QVDVVYKVKE
     RNTGSFNFGI GYGTESGVSF QAGVQQDNWL GTGYAVGING TKNDYQTYTE LSVTNPYFTV
     DGVSLGGRIF YNDFDANDAD LSDYTNKSYG TDVTLGFPVN EYNTLRAGVG YVHNSLSNMQ
     PQVAMWRYLN SMGQYPDNTN DRNSFSANDF TFNYGWTYNK LDRGFFPTEG SRVNLNGKVT
     IPGSDNEYYK ATLDTATYVP IDNDHQWVVL GRTRFGYGDG IGGKEMPFYE NFYAGGSSTV
     RGFQSNTIGP KAVYFPSSSR HDGDSGYTND CKSTESAPCK SDDAVGGNAM AVASLELITP
     TPFISDKYAN SVRTSVFWDM GTVWDTHWDS NAYGGYPDYS DPSNIRMSAG IAVQWMSPLG
     PLVFSYAQPF KKYDGDKAEQ FQFNIGKTW