ID   BAMA_PECAS              Reviewed;         814 AA.
AC   Q6D8D5;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE   Flags: Precursor;
GN   Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN   OrderedLocusNames=ECA1039;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC       involved in assembly and insertion of beta-barrel proteins into the
CC       outer membrane. Constitutes, with BamD, the core component of the
CC       assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC       membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC       {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
CC   -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
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DR   EMBL; BX950851; CAG73950.1; -; Genomic_DNA.
DR   RefSeq; WP_011092637.1; NC_004547.2.
DR   AlphaFoldDB; Q6D8D5; -.
DR   SMR; Q6D8D5; -.
DR   STRING; 218491.ECA1039; -.
DR   EnsemblBacteria; CAG73950; CAG73950; ECA1039.
DR   GeneID; 57207868; -.
DR   KEGG; eca:ECA1039; -.
DR   PATRIC; fig|218491.5.peg.1047; -.
DR   eggNOG; COG4775; Bacteria.
DR   HOGENOM; CLU_007664_1_0_6; -.
DR   OMA; IFMPAFG; -.
DR   OrthoDB; 258122at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01430; OM_assembly_BamA; 1.
DR   InterPro; IPR000184; Bac_surfAg_D15.
DR   InterPro; IPR010827; BamA/TamA_POTRA.
DR   InterPro; IPR039910; D15-like.
DR   InterPro; IPR023707; OM_assembly_BamA.
DR   InterPro; IPR034746; POTRA.
DR   PANTHER; PTHR12815; PTHR12815; 1.
DR   PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR   Pfam; PF01103; Omp85; 1.
DR   Pfam; PF07244; POTRA; 4.
DR   PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR   TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR   PROSITE; PS51779; POTRA; 5.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Repeat; Signal;
KW   Transmembrane; Transmembrane beta strand.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT   CHAIN           21..814
FT                   /note="Outer membrane protein assembly factor BamA"
FT                   /id="PRO_0000045371"
FT   DOMAIN          24..91
FT                   /note="POTRA 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          92..172
FT                   /note="POTRA 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          175..263
FT                   /note="POTRA 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          266..344
FT                   /note="POTRA 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          347..421
FT                   /note="POTRA 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ   SEQUENCE   814 AA;  89626 MW;  2D8F3A21737628F5 CRC64;
     MAIKKLLIAS LLFSSATVYG ADGFVVKDIH FEGLQRVAVG AALLSMPVRV GDTIGDDDIG
     NTIRALFATG NFEDVRVLRD GETLIVQVKE RPTIASVTFS GNKSVKDDML KENLEASGVR
     VGEALDRTAL TSIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFT EGVSAKIQQI
     NIVGNKAFSS DELISRFQLR DEVPWWNVVG DRKYQKQKLS GDLETLRSFY LDRGYARFNI
     DSTQVSLTPD KKGIYITINM TEGEQYKLSG VAVKGNLAGH SAEIEGLTKV EPGELYNGTK
     VTRMEEDIKK LLGRYGYAYP RVVTQPEIND ADKTVRLNIN VDAGNRFYVR HVRFDGNDTS
     KDTVLRREMR QMEGAWLGND LVEQGKERLN RLGYFESVEV ETQRVPGVAD QVDVTYKVKE
     RNTGTFNFGV GFGTESGVSF QAGVQQDNWL GTGNSVGISG TKNDYQTYVE LSLTDPYFTV
     DGVSLGGRVF YNKFEASDAD LSDYTNVSYG VGSTLGFPIN ENNSLRVGLD YVHNDLSDMR
     PQVSMWRYLD SVGVNPSVVG ENVKSSADFK ANDFFLNTGW SYNNLDRGYF PTKGTRASAN
     AKIAVPGSDN EYYKLTFDSA SYYPLTESGK WVVMGRTRAG FADGIGSKEV PFYDNFYAGG
     SSTVRGFQSN TIGPKAAYYK CPANLVGSGF NSYSGCPIDS TNMDDAVGGN AMAVLSAELI
     VPTPFISDKY ANSVRTSFFV DGGTVWDTNW ENTAETLKAG VPDYGKATNF RVSSGIALQW
     MSPLGPLVFS YAQPVKKYDG DKSEQFQFNI GKTW