BAMA_SALTI
ID BAMA_SALTI Reviewed; 803 AA.
AC Q8Z9A3; Q7CBP9;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE Flags: Precursor;
GN Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN OrderedLocusNames=STY0247, t0225;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. Constitutes, with BamD, the core component of the
CC assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
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DR EMBL; AL513382; CAD08682.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO67955.1; -; Genomic_DNA.
DR RefSeq; NP_454831.1; NC_003198.1.
DR RefSeq; WP_001240921.1; NZ_WSUR01000009.1.
DR AlphaFoldDB; Q8Z9A3; -.
DR SMR; Q8Z9A3; -.
DR STRING; 220341.16501505; -.
DR EnsemblBacteria; AAO67955; AAO67955; t0225.
DR KEGG; stt:t0225; -.
DR KEGG; sty:STY0247; -.
DR PATRIC; fig|220341.7.peg.247; -.
DR eggNOG; COG4775; Bacteria.
DR HOGENOM; CLU_007664_1_0_6; -.
DR OMA; IFMPAFG; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR PANTHER; PTHR12815; PTHR12815; 1.
DR PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Repeat; Signal; Transmembrane;
KW Transmembrane beta strand.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT CHAIN 21..803
FT /note="Outer membrane protein assembly factor BamA"
FT /id="PRO_0000045376"
FT DOMAIN 24..91
FT /note="POTRA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 92..172
FT /note="POTRA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 175..263
FT /note="POTRA 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 266..344
FT /note="POTRA 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 347..421
FT /note="POTRA 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ SEQUENCE 803 AA; 89467 MW; BBF8670070E67628 CRC64;
MAMKKLLIAS LLFSSATVYG AEGFVVKDIH FEGLQRVAVG AALLSMPVRT GDTVNDEDIS
NTIRALFATG NFEDVRVLRD GNTLLVQVKE RPTIASITFS GNKSVKDDML KQNLEASGVR
VGESLDRTTL SDIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFQ EGVSAKIQQI
NIVGNHAFST EELISHFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSYY LDRGYARFNI
DSTQVSLTPD KKGIYITVNI TEGDQYKLSG VQVSGNLAGH SAEIEKLTKI EPGELYNGTK
VTKMEDDIKK LLGRYGYAYP RVQSQPEIND ADKTVKLRVN VDAGNRFYVR KIRFEGNDTS
KDSVLRREMR QMEGAWLGSD LVDQGKERLN RLGFFETVDT DTQRVPGSPD QVDVVYKVKE
RNTGSFNFGI GYGTESGVSF QAGVQQDNWL GTGYSVGING TKNDYQTYSE LSVTNPYFTV
DGVSLGGRIF YNDFEADDAD LSDYTNKSYG TDVTLGFPIN EYNTLRAGLG YVHNKLSNMQ
PQIAMDRYLE SMGDPDASDF AADDFTFNYG WTYNKLDRGY FPTDGSRVNL TGKVTIPGSD
NEYYKVSLDT ATYVPIDNDH KWVVLGRTRW GYGDGLGGKE MPFYENFYAG GSSTVRGFQS
NTIGPKAVYK NGAHTSWDDD DDYEDCTQES GCKSDDAVGG NAMAVASLEF ITPTPFISEK
YANSVRTSFF WDMGTVWDTN WDPSSAPSDV PDYSDPGNIR MSAGIALQWM SPLGPLVFSY
AQPFKKYDGD KAEQFQFNIG KTW
