BAMA_SALTY
ID BAMA_SALTY Reviewed; 804 AA.
AC Q8ZRP0;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE Flags: Precursor;
GN Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN OrderedLocusNames=STM0224;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. Constitutes, with BamD, the core component of the
CC assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
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DR EMBL; AE006468; AAL19188.1; -; Genomic_DNA.
DR RefSeq; NP_459229.1; NC_003197.2.
DR RefSeq; WP_001240935.1; NC_003197.2.
DR PDB; 5OR1; X-ray; 2.92 A; A=1-804.
DR PDBsum; 5OR1; -.
DR AlphaFoldDB; Q8ZRP0; -.
DR SMR; Q8ZRP0; -.
DR STRING; 99287.STM0224; -.
DR PaxDb; Q8ZRP0; -.
DR EnsemblBacteria; AAL19188; AAL19188; STM0224.
DR GeneID; 1251742; -.
DR KEGG; stm:STM0224; -.
DR PATRIC; fig|99287.12.peg.237; -.
DR HOGENOM; CLU_007664_1_0_6; -.
DR OMA; IFMPAFG; -.
DR PhylomeDB; Q8ZRP0; -.
DR BioCyc; SENT99287:STM0224-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:1990063; C:Bam protein complex; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IBA:GO_Central.
DR GO; GO:0051205; P:protein insertion into membrane; IBA:GO_Central.
DR DisProt; DP02483; -.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR PANTHER; PTHR12815; PTHR12815; 1.
DR PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 1: Evidence at protein level;
KW 3D-structure; Cell outer membrane; Membrane; Reference proteome; Repeat;
KW Signal; Transmembrane; Transmembrane beta strand.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT CHAIN 21..804
FT /note="Outer membrane protein assembly factor BamA"
FT /id="PRO_0000045377"
FT DOMAIN 24..91
FT /note="POTRA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 92..172
FT /note="POTRA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 175..263
FT /note="POTRA 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 266..344
FT /note="POTRA 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 347..421
FT /note="POTRA 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT STRAND 431..433
FT /evidence="ECO:0007829|PDB:5OR1"
FT TURN 434..436
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 437..439
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 442..448
FT /evidence="ECO:0007829|PDB:5OR1"
FT HELIX 449..451
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 455..461
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 464..475
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 484..495
FT /evidence="ECO:0007829|PDB:5OR1"
FT TURN 496..500
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 501..503
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 508..517
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 520..533
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 535..537
FT /evidence="ECO:0007829|PDB:5OR1"
FT HELIX 543..551
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 565..575
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 578..582
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 585..596
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 604..618
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 623..633
FT /evidence="ECO:0007829|PDB:5OR1"
FT HELIX 644..646
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 655..659
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 676..678
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 701..713
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 719..721
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 728..738
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 745..748
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 761..772
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 775..786
FT /evidence="ECO:0007829|PDB:5OR1"
FT STRAND 796..800
FT /evidence="ECO:0007829|PDB:5OR1"
SQ SEQUENCE 804 AA; 89527 MW; 6197447548FAC41E CRC64;
MAMKKLLIAS LLFSSATVYG AEGFVVKDIH FEGLQRVAVG AALLSMPVRT GDTVNDEDIS
NTIRALFATG NFEDVRVLRD GNTLLVQVKE RPTIASITFS GNKSVKDDML KQNLEASGVR
VGESLDRTTL SDIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFQ EGVSAKIQQI
NIVGNHAFST EELISHFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSYY LDRGYARFNI
DSTQVSLTPD KKGIYITVNI TEGDQYKLSG VQVSGNLAGH SAEIENLTKI EPGELYNGTK
VTKMEDDIKK LLGRYGYAYP RVQSQPEIND ADKTVKLRVN VDAGNRFYVR KIRFEGNDTS
KDSVLRREMR QMEGAWLGSD LVDQGKERLN RLGFFETVDT DTQRVPGSPD QVDVVYKVKE
RNTGSFNFGI GYGTESGVSF QAGVQQDNWL GTGYSVGING TKNDYQTYSE LSVTNPYFTV
DGVSLGGRIF YNDFQADDAD LSDYTNKSYG TDVTLGFPIN EYNTLRAGLG YVHNKLSNMQ
PQIAMDRYLE SMGQSADTSS FAADDFTFNY GWTYNKLDRG YFPTDGSRVN LTGKVTIPGS
DNEYYKVSLD TATYVPIDND HKWVVLGRTR WGYGDGLGGK EMPFYENFYA GGSSTVRGFQ
SNTIGPKAVY KNGAHTSWDD NDDYEDCTQE SGCKSDDAVG GNAMAVASLE FITPTPFISE
KYANSVRTSF FWDMGTVWDT NWDPSSAPSD VPDYSDPGNI RMSAGIALQW MSPLGPLVFS
YAQPFKKYDG DKAEQFQFNI GKTW
