BAMA_SHIFL
ID BAMA_SHIFL Reviewed; 810 AA.
AC P0A943; P39170; P39181; P77465; Q549H3;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE Flags: Precursor;
GN Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=oma90, yaeT;
GN OrderedLocusNames=SF0167, S0170;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RC STRAIN=M90T / Serotype 5a;
RX PubMed=11179681; DOI=10.1016/s0378-1119(00)00537-0;
RA Robb C.W., Orihuela C.J., Ekkelenkamp M.B., Niesel D.W.;
RT "Identification and characterization of an in vivo regulated D15/Oma87
RT homologue in Shigella flexneri using differential display polymerase chain
RT reaction.";
RL Gene 262:169-177(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. Constitutes, with BamD, the core component of the
CC assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
CC -!- INDUCTION: Up-regulated during intraperitoneal growth.
CC {ECO:0000269|PubMed:11179681}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF120927; AAD23568.1; -; Genomic_DNA.
DR EMBL; AE005674; AAN41829.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP15710.1; -; Genomic_DNA.
DR RefSeq; NP_706122.1; NC_004337.2.
DR RefSeq; WP_001240896.1; NZ_WPGW01000006.1.
DR AlphaFoldDB; P0A943; -.
DR SMR; P0A943; -.
DR STRING; 198214.SF0167; -.
DR TCDB; 1.B.33.1.3; the outer membrane protein insertion porin (bam complex) (ompip) family.
DR EnsemblBacteria; AAN41829; AAN41829; SF0167.
DR EnsemblBacteria; AAP15710; AAP15710; S0170.
DR GeneID; 1024444; -.
DR GeneID; 66671535; -.
DR KEGG; sfl:SF0167; -.
DR KEGG; sfx:S0170; -.
DR PATRIC; fig|198214.7.peg.189; -.
DR HOGENOM; CLU_007664_1_0_6; -.
DR OMA; IFMPAFG; -.
DR OrthoDB; 258122at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR PANTHER; PTHR12815; PTHR12815; 1.
DR PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 2: Evidence at transcript level;
KW Cell outer membrane; Membrane; Reference proteome; Repeat; Signal;
KW Transmembrane; Transmembrane beta strand.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT CHAIN 21..810
FT /note="Outer membrane protein assembly factor BamA"
FT /id="PRO_0000033473"
FT DOMAIN 24..91
FT /note="POTRA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 92..172
FT /note="POTRA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 175..263
FT /note="POTRA 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 266..344
FT /note="POTRA 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 347..421
FT /note="POTRA 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ SEQUENCE 810 AA; 90553 MW; DDCE4C6D341664EB CRC64;
MAMKKLLIAS LLFSSATVYG AEGFVVKDIH FEGLQRVAVG AALLSMPVRT GDTVNDEDIS
NTIRALFATG NFEDVRVLRD GDTLLVQVKE RPTIASITFS GNKSVKDDML KQNLEASGVR
VGESLDRTTI ADIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFQ EGVSAEIQQI
NIVGNHAFTT DELISHFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSYY LDRGYARFNI
DSTQVSLTPD KKGIYVTVNI TEGDQYKLSG VEVSGNLAGH SAEIEQLTKI EPGELYNGTK
VTKMEDDIKK LLGRYGYAYP RVQSMPEIND ADKTVKLRVN VDAGNRFYVR KIRFEGNDTS
KDAVLRREMR QMEGAWLGSD LVDQGKERLN RLGFFETVDT DTQRVPGSPD QVDVVYKVKE
RNTGSFNFGI GYGTESGVSF QAGVQQDNWL GTGYAVGING TKNDYQTYAE LSVTNPYFTV
DGVSLGGRLF YNDFQADDAD LSDYTNKSYG TDVTLGFPIN EYNSLRAGLG YVHNSLSNMQ
PQVAMWRYLY SMGEHPSTSD QDNSFKTDDF TFNYGWTYNK LDRGYFPTDG SRVNLTGKVT
IPGSDNEYYK VTLDTATYVP IDDDHKWVVL GRTRWGYGDG LGGKEMPFYE NFYAGGSSTV
RGFQSNTIGP KAVYFPHQAS NYDPDYDYEC ATQDGAKDLC KSDDAVGGNA MAVASLEFIT
PTPFISDKYA NSVRTSFFWD MGTVWDTNWD SSQYSGYPDY SDPSNIRMSA GIALQWMSPL
GPLVFSYAQP FKKYDGDKAE QFQFNIGKTW
