ID   RS4_PSEAE               Reviewed;         206 AA.
AC   O52759;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   08-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=30S ribosomal protein S4 {ECO:0000255|HAMAP-Rule:MF_01306};
GN   Name=rpsD {ECO:0000255|HAMAP-Rule:MF_01306}; OrderedLocusNames=PA4239;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 189-206.
RC   STRAIN=FRD1;
RX   PubMed=10368148; DOI=10.1128/jb.181.12.3730-3742.1999;
RA   Ma J.-F., Ochsner U.A., Klotz M.G., Nanayakkara V.K., Howell M.L.,
RA   Johnson Z., Posey J.E., Vasil M.L., Monaco J.J., Hassett D.J.;
RT   "Bacterioferritin A modulates catalase A (KatA) activity and resistance to
RT   hydrogen peroxide in Pseudomonas aeruginosa.";
RL   J. Bacteriol. 181:3730-3742(1999).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CC       {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- FUNCTION: With S5 and S12 plays an important role in translational
CC       accuracy. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts protein S5. The
CC       interaction surface between S4 and S5 is involved in control of
CC       translational fidelity. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004091; AAG07627.1; -; Genomic_DNA.
DR   EMBL; AF047025; AAC03115.1; -; Genomic_DNA.
DR   PIR; E83113; E83113.
DR   RefSeq; NP_252929.1; NC_002516.2.
DR   RefSeq; WP_003093678.1; NZ_QZGE01000028.1.
DR   AlphaFoldDB; O52759; -.
DR   SMR; O52759; -.
DR   STRING; 287.DR97_3672; -.
DR   PaxDb; O52759; -.
DR   PRIDE; O52759; -.
DR   DNASU; 881814; -.
DR   EnsemblBacteria; AAG07627; AAG07627; PA4239.
DR   GeneID; 881814; -.
DR   KEGG; pae:PA4239; -.
DR   PATRIC; fig|208964.12.peg.4440; -.
DR   PseudoCAP; PA4239; -.
DR   HOGENOM; CLU_092403_0_2_6; -.
DR   InParanoid; O52759; -.
DR   OMA; NVVFRMG; -.
DR   PhylomeDB; O52759; -.
DR   BioCyc; PAER208964:G1FZ6-4312-MON; -.
DR   PRO; PR:O52759; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0045903; P:positive regulation of translational fidelity; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_01306_B; Ribosomal_S4_B; 1.
DR   InterPro; IPR022801; Ribosomal_S4/S9.
DR   InterPro; IPR001912; Ribosomal_S4/S9_N.
DR   InterPro; IPR005709; Ribosomal_S4_bac-type.
DR   InterPro; IPR018079; Ribosomal_S4_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11831; PTHR11831; 1.
DR   PANTHER; PTHR11831:SF4; PTHR11831:SF4; 1.
DR   Pfam; PF00163; Ribosomal_S4; 1.
DR   Pfam; PF01479; S4; 1.
DR   SMART; SM01390; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   TIGRFAMs; TIGR01017; rpsD_bact; 1.
DR   PROSITE; PS00632; RIBOSOMAL_S4; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..206
FT                   /note="30S ribosomal protein S4"
FT                   /id="PRO_0000132438"
FT   DOMAIN          96..156
FT                   /note="S4 RNA-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01306"
FT   CONFLICT        189..194
FT                   /note="SDLSAD -> NSSSVP (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   206 AA;  23278 MW;  DBDB5D0191723186 CRC64;
     MARYIGPKCK LSRREGTDLF LKSGARALDS KCKAENVPGQ HGQRRGRLSD YGLQLREKQK
     VRRIYGVLER QFRGYYQEAS RRKGSTGENL LQLLECRLDN VVYRMGFGST RSESRQLVSH
     KAITVNGQTV NIPSYQVKAG DVVAVREKSK NQLRIAQALE LCGQRGRVEW VEVDLDKKAG
     TFKSAPARSD LSADINENLI VELYSK