RS4_PYRAB
ID RS4_PYRAB Reviewed; 180 AA.
AC P61992; G8ZGN8; Q9V199;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2004, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=30S ribosomal protein S4 {ECO:0000255|HAMAP-Rule:MF_01306};
GN Name=rps4 {ECO:0000255|HAMAP-Rule:MF_01306}; OrderedLocusNames=PYRAB05280;
GN ORFNames=PAB0361;
OS Pyrococcus abyssi (strain GE5 / Orsay).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=272844;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GE5 / Orsay;
RX PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA Weissenbach J., Zivanovic Y., Forterre P.;
RT "An integrated analysis of the genome of the hyperthermophilic archaeon
RT Pyrococcus abyssi.";
RL Mol. Microbiol. 47:1495-1512(2003).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=GE5 / Orsay;
RX PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA Gao J., Wang J.;
RT "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT Pyrococcus furiosus DSM 3638.";
RL Curr. Microbiol. 64:118-129(2012).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CC {ECO:0000255|HAMAP-Rule:MF_01306}.
CC -!- FUNCTION: With S5 and S12 plays an important role in translational
CC accuracy. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts protein S5. The
CC interaction surface between S4 and S5 is involved in control of
CC translational fidelity. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC {ECO:0000255|HAMAP-Rule:MF_01306}.
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DR EMBL; AJ248284; CAB49450.1; -; Genomic_DNA.
DR EMBL; HE613800; CCE69917.1; -; Genomic_DNA.
DR PIR; C75171; C75171.
DR RefSeq; WP_010867652.1; NC_000868.1.
DR PDB; 5JB3; EM; 5.34 A; D=1-180.
DR PDB; 5JBH; EM; 5.34 A; D=1-180.
DR PDB; 6SW9; EM; 4.20 A; D=1-180.
DR PDB; 6SWC; EM; 3.30 A; D=1-180.
DR PDB; 6SWD; EM; 3.20 A; D=1-180.
DR PDBsum; 5JB3; -.
DR PDBsum; 5JBH; -.
DR PDBsum; 6SW9; -.
DR PDBsum; 6SWC; -.
DR PDBsum; 6SWD; -.
DR AlphaFoldDB; P61992; -.
DR SMR; P61992; -.
DR STRING; 272844.PAB0361; -.
DR EnsemblBacteria; CAB49450; CAB49450; PAB0361.
DR GeneID; 41713476; -.
DR KEGG; pab:PAB0361; -.
DR PATRIC; fig|272844.11.peg.563; -.
DR eggNOG; arCOG04239; Archaea.
DR HOGENOM; CLU_089738_1_1_2; -.
DR OMA; ARQFITH; -.
DR OrthoDB; 93256at2157; -.
DR PhylomeDB; P61992; -.
DR Proteomes; UP000000810; Chromosome.
DR Proteomes; UP000009139; Chromosome.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; -; 1.
DR HAMAP; MF_01306_A; Ribosomal_S4_A; 1.
DR InterPro; IPR022801; Ribosomal_S4/S9.
DR InterPro; IPR005710; Ribosomal_S4/S9_euk/arc.
DR InterPro; IPR001912; Ribosomal_S4/S9_N.
DR InterPro; IPR022802; Ribosomal_S4_arc.
DR InterPro; IPR018079; Ribosomal_S4_CS.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR11831; PTHR11831; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM01390; Ribosomal_S4; 1.
DR SMART; SM00363; S4; 1.
DR TIGRFAMs; TIGR01018; uS4_arch; 1.
DR PROSITE; PS00632; RIBOSOMAL_S4; 1.
DR PROSITE; PS50889; S4; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..180
FT /note="30S ribosomal protein S4"
FT /id="PRO_0000132515"
FT DOMAIN 103..174
FT /note="S4 RNA-binding"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01306"
FT STRAND 15..17
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 20..33
FT /evidence="ECO:0007829|PDB:6SWD"
FT STRAND 36..38
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 39..55
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 57..60
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 64..79
FT /evidence="ECO:0007829|PDB:6SWD"
FT STRAND 80..83
FT /evidence="ECO:0007829|PDB:6SWC"
FT HELIX 89..91
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 97..99
FT /evidence="ECO:0007829|PDB:6SWD"
FT TURN 100..102
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 105..110
FT /evidence="ECO:0007829|PDB:6SWD"
FT TURN 111..113
FT /evidence="ECO:0007829|PDB:6SWD"
FT STRAND 114..117
FT /evidence="ECO:0007829|PDB:6SWD"
FT HELIX 118..126
FT /evidence="ECO:0007829|PDB:6SWD"
FT STRAND 130..135
FT /evidence="ECO:0007829|PDB:6SWD"
FT STRAND 149..154
FT /evidence="ECO:0007829|PDB:6SWD"
FT TURN 166..174
FT /evidence="ECO:0007829|PDB:6SWD"
SQ SEQUENCE 180 AA; 21338 MW; D59E61EF49F6CE57 CRC64;
MGDPKRQRKK YETPPHPWIK ERLDRERVLM DKYELKNKKE LWKHETQLKN FRRRARRLLA
ARGKQAEIER EQLLARLKRL GLLPEDAVLD DVLSLTIEDI LERRLQTIVY KKGLARTMRQ
ARQLIVHGHI EVNGQIIRSP SYLVLKEEED TITYARTSPF ANPQHPERMM IEKAKQGGEA
