BAMA_YERPE
ID BAMA_YERPE Reviewed; 795 AA.
AC Q8ZH58; Q0WHZ3; Q74S49; Q7CH17;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE Flags: Precursor;
GN Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN OrderedLocusNames=YPO1052, y3127, YP_2798;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. Constitutes, with BamD, the core component of the
CC assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC {ECO:0000255|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC Rule:MF_01430}.
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DR EMBL; AL590842; CAL19717.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM86677.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS62982.1; -; Genomic_DNA.
DR PIR; AC0129; AC0129.
DR RefSeq; WP_002212139.1; NZ_WUCM01000044.1.
DR RefSeq; YP_002346095.1; NC_003143.1.
DR AlphaFoldDB; Q8ZH58; -.
DR SMR; Q8ZH58; -.
DR IntAct; Q8ZH58; 1.
DR STRING; 214092.YPO1052; -.
DR PaxDb; Q8ZH58; -.
DR DNASU; 1148074; -.
DR EnsemblBacteria; AAM86677; AAM86677; y3127.
DR EnsemblBacteria; AAS62982; AAS62982; YP_2798.
DR GeneID; 66844576; -.
DR KEGG; ype:YPO1052; -.
DR KEGG; ypk:y3127; -.
DR KEGG; ypm:YP_2798; -.
DR PATRIC; fig|214092.21.peg.1340; -.
DR eggNOG; COG4775; Bacteria.
DR HOGENOM; CLU_007664_1_0_6; -.
DR OMA; IFMPAFG; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:1990063; C:Bam protein complex; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IBA:GO_Central.
DR GO; GO:0051205; P:protein insertion into membrane; IBA:GO_Central.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR PANTHER; PTHR12815; PTHR12815; 1.
DR PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Reference proteome; Repeat; Signal;
KW Transmembrane; Transmembrane beta strand.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT CHAIN 21..795
FT /note="Outer membrane protein assembly factor BamA"
FT /id="PRO_0000045379"
FT DOMAIN 24..91
FT /note="POTRA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 92..172
FT /note="POTRA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 175..263
FT /note="POTRA 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 266..344
FT /note="POTRA 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT DOMAIN 347..421
FT /note="POTRA 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ SEQUENCE 795 AA; 87838 MW; 8C4581328D38F821 CRC64;
MAMKKLLIAS LLFGSATVYG ADGFVVNDIH FEGLQRVAVG AALLNMPVRV GDTVSDDDIG
KTIRALFATG NFEDVRVLRD GNTLIVQVKE RPTIASITFS GNKAVKEDML KQNLEASGVR
VGEALDRTTI SNIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFT EGVSAKIQQI
NIVGNHSFTT DELISRFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSFY LDRGYARFNI
DSTQVSLTPD KKGIYVTINI TEGPQFKLNS VIVSGNLAGH QSEAEKLTKI EPGELFNGSK
VTRMEDDIKK MLGRYGYAYP RVVTQPEIND DDKTVKLHIN VDAGNRFYVR HIRFEGNDTS
KDSVLRREMR QMEGAWLGND QVEAGKERLN RLGYFETVDV ETQRVPGAAD LVDVTYKVKE
RNTGSLNFGI GYGTESGVSF QVGVQQDNWL GTGNTVGING TKNDYQTYAE FTLMDPYFTV
DGVSLGGRIF YNDFKADNAD LSGYTNSSYG ADGTLGFPIN ENNSLRVGVG YVHNDLSDML
PQVAMWRYLE SVGERPGYDG REGFTTDDFT LNLGWTYNNL DRGFFPTSGV KSSVNTKITV
PGSDNEFYKV TFDTSAYQPL NEDRSWVLLG RGRLGYGDGI GSKEMPFYEN FYAGGSSTVR
GFRSNNIGPK AAYYANGGAT VTNSTDAVGG NAMAVASIEL ITPTPFISEK YSNSVRTSIF
IDSGTVWDTN WENTAKTRAA GIPDYGKASN IRVSAGVALQ WMSPLGPLVF SYAKPVKDYE
GDKSEQFQFN IGKTW
