ID   BAMA_YERPN              Reviewed;         795 AA.
AC   Q1CFF5; C4GWX4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000255|HAMAP-Rule:MF_01430};
DE   Flags: Precursor;
GN   Name=bamA {ECO:0000255|HAMAP-Rule:MF_01430}; Synonyms=yaeT;
GN   OrderedLocusNames=YPN_2948; ORFNames=YP516_3338;
OS   Yersinia pestis bv. Antiqua (strain Nepal516).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=377628;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RA   Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L.,
RA   Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R.,
RA   Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.;
RT   "Yersinia pestis Nepal516A whole genome shotgun sequencing project.";
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC       involved in assembly and insertion of beta-barrel proteins into the
CC       outer membrane. Constitutes, with BamD, the core component of the
CC       assembly machinery. {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBUNIT: Part of the Bam complex, which is composed of the outer
CC       membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
CC       {ECO:0000255|HAMAP-Rule:MF_01430}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
CC   -!- SIMILARITY: Belongs to the BamA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01430}.
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DR   EMBL; CP000305; ABG19275.1; -; Genomic_DNA.
DR   EMBL; ACNQ01000017; EEO75424.1; -; Genomic_DNA.
DR   RefSeq; WP_002212139.1; NZ_ACNQ01000017.1.
DR   AlphaFoldDB; Q1CFF5; -.
DR   SMR; Q1CFF5; -.
DR   EnsemblBacteria; ABG19275; ABG19275; YPN_2948.
DR   GeneID; 66844576; -.
DR   KEGG; ypn:YPN_2948; -.
DR   HOGENOM; CLU_007664_1_0_6; -.
DR   OMA; IFMPAFG; -.
DR   Proteomes; UP000008936; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01430; OM_assembly_BamA; 1.
DR   InterPro; IPR000184; Bac_surfAg_D15.
DR   InterPro; IPR010827; BamA/TamA_POTRA.
DR   InterPro; IPR039910; D15-like.
DR   InterPro; IPR023707; OM_assembly_BamA.
DR   InterPro; IPR034746; POTRA.
DR   PANTHER; PTHR12815; PTHR12815; 1.
DR   PANTHER; PTHR12815:SF23; PTHR12815:SF23; 1.
DR   Pfam; PF01103; Omp85; 1.
DR   Pfam; PF07244; POTRA; 4.
DR   PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR   TIGRFAMs; TIGR03303; OM_YaeT; 1.
DR   PROSITE; PS51779; POTRA; 5.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Repeat; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01430"
FT   CHAIN           21..795
FT                   /note="Outer membrane protein assembly factor BamA"
FT                   /id="PRO_5000115528"
FT   DOMAIN          24..91
FT                   /note="POTRA 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          92..172
FT                   /note="POTRA 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          175..263
FT                   /note="POTRA 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          266..344
FT                   /note="POTRA 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   DOMAIN          347..421
FT                   /note="POTRA 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
SQ   SEQUENCE   795 AA;  87838 MW;  8C4581328D38F821 CRC64;
     MAMKKLLIAS LLFGSATVYG ADGFVVNDIH FEGLQRVAVG AALLNMPVRV GDTVSDDDIG
     KTIRALFATG NFEDVRVLRD GNTLIVQVKE RPTIASITFS GNKAVKEDML KQNLEASGVR
     VGEALDRTTI SNIEKGLEDF YYSVGKYSAS VKAVVTPLPR NRVDLKLVFT EGVSAKIQQI
     NIVGNHSFTT DELISRFQLR DEVPWWNVVG DRKYQKQKLA GDLETLRSFY LDRGYARFNI
     DSTQVSLTPD KKGIYVTINI TEGPQFKLNS VIVSGNLAGH QSEAEKLTKI EPGELFNGSK
     VTRMEDDIKK MLGRYGYAYP RVVTQPEIND DDKTVKLHIN VDAGNRFYVR HIRFEGNDTS
     KDSVLRREMR QMEGAWLGND QVEAGKERLN RLGYFETVDV ETQRVPGAAD LVDVTYKVKE
     RNTGSLNFGI GYGTESGVSF QVGVQQDNWL GTGNTVGING TKNDYQTYAE FTLMDPYFTV
     DGVSLGGRIF YNDFKADNAD LSGYTNSSYG ADGTLGFPIN ENNSLRVGVG YVHNDLSDML
     PQVAMWRYLE SVGERPGYDG REGFTTDDFT LNLGWTYNNL DRGFFPTSGV KSSVNTKITV
     PGSDNEFYKV TFDTSAYQPL NEDRSWVLLG RGRLGYGDGI GSKEMPFYEN FYAGGSSTVR
     GFRSNNIGPK AAYYANGGAT VTNSTDAVGG NAMAVASIEL ITPTPFISEK YSNSVRTSIF
     IDSGTVWDTN WENTAKTRAA GIPDYGKASN IRVSAGVALQ WMSPLGPLVF SYAKPVKDYE
     GDKSEQFQFN IGKTW