ID   RS4_SULAC               Reviewed;         176 AA.
AC   P39467; Q4JCH1;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 3.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=30S ribosomal protein S4;
GN   Name=rps4; OrderedLocusNames=Saci_0081;
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS   15157 / NCIMB 11770).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=7597027; DOI=10.1073/pnas.92.13.5768;
RA   Langer D., Hain J., Thuriaux P., Zillig W.;
RT   "Transcription in archaea: similarity to that in eucarya.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:5768-5772(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=15995215; DOI=10.1128/jb.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CC       {ECO:0000250}.
CC   -!- FUNCTION: With S5 and S12 plays an important role in translational
CC       accuracy. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts protein S5. The
CC       interaction surface between S4 and S5 is involved in control of
CC       translational fidelity (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA56478.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X80194; CAA56478.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP000077; AAY79508.1; -; Genomic_DNA.
DR   RefSeq; WP_011277009.1; NC_007181.1.
DR   AlphaFoldDB; P39467; -.
DR   SMR; P39467; -.
DR   STRING; 330779.Saci_0081; -.
DR   EnsemblBacteria; AAY79508; AAY79508; Saci_0081.
DR   GeneID; 3473857; -.
DR   KEGG; sai:Saci_0081; -.
DR   PATRIC; fig|330779.12.peg.75; -.
DR   eggNOG; arCOG04239; Archaea.
DR   HOGENOM; CLU_089738_1_1_2; -.
DR   OMA; ARQFITH; -.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_01306_A; Ribosomal_S4_A; 1.
DR   InterPro; IPR022801; Ribosomal_S4/S9.
DR   InterPro; IPR005710; Ribosomal_S4/S9_euk/arc.
DR   InterPro; IPR001912; Ribosomal_S4/S9_N.
DR   InterPro; IPR022802; Ribosomal_S4_arc.
DR   InterPro; IPR018079; Ribosomal_S4_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11831; PTHR11831; 1.
DR   Pfam; PF01479; S4; 1.
DR   SMART; SM01390; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   TIGRFAMs; TIGR01018; uS4_arch; 1.
DR   PROSITE; PS00632; RIBOSOMAL_S4; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..176
FT                   /note="30S ribosomal protein S4"
FT                   /id="PRO_0000132520"
FT   DOMAIN          104..166
FT                   /note="S4 RNA-binding"
FT   CONFLICT        164..176
FT                   /note="NPPSQGEVNVEQA -> KIHHHKVR (in Ref. 1; CAA56478)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   176 AA;  20422 MW;  D3F365EE3B36027F CRC64;
     MGDPRKSKKK WMGPSHPWIK INLGKEQILI GKYGLRNKKE IWIAQTMIRN FRHQARSLLA
     LPPAERNIRE KQLIQKLYRM GILEKDNSTL DDILSLTEEN YLERRLQTIV YKKGLARTIY
     QARQLITHGH IAISGRKVTS PGYVVLRGEE DLIDYYPTSP FKQNPPSQGE VNVEQA