ID   RS4_XENLA               Reviewed;         263 AA.
AC   P49401; Q3B893; Q6NRW9;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 4.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=40S ribosomal protein S4;
GN   Name=rps4; Synonyms=rps4x;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung, and Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 112-144.
RX   PubMed=1579486; DOI=10.1093/nar/20.8.1859;
RA   Loreni F., Francesconi A., Jappelli R., Amaldi F.;
RT   "Analysis of mRNAs under translational control during Xenopus
RT   embryogenesis: isolation of new ribosomal protein clones.";
RL   Nucleic Acids Res. 20:1859-1863(1992).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000305}.
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DR   EMBL; BC070591; AAH70591.1; -; mRNA.
DR   EMBL; BC106700; AAI06701.1; -; mRNA.
DR   EMBL; X64206; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; S22608; S22608.
DR   RefSeq; NP_001084941.1; NM_001091472.1.
DR   RefSeq; NP_001090472.1; NM_001097003.1.
DR   RefSeq; XP_018087661.1; XM_018232172.1.
DR   AlphaFoldDB; P49401; -.
DR   SMR; P49401; -.
DR   BioGRID; 101364; 2.
DR   IntAct; P49401; 1.
DR   DNASU; 431998; -.
DR   GeneID; 431998; -.
DR   GeneID; 779385; -.
DR   KEGG; xla:431998; -.
DR   KEGG; xla:779385; -.
DR   CTD; 431998; -.
DR   CTD; 779385; -.
DR   Xenbase; XB-GENE-17346803; rps4x.L.
DR   Xenbase; XB-GENE-967208; rps4x.S.
DR   OMA; FPVGLMD; -.
DR   OrthoDB; 1065966at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Proteomes; UP000186698; Chromosome 8S.
DR   Bgee; 431998; Expressed in testis and 19 other tissues.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR032277; 40S_S4_C.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 1.
DR   Pfam; PF16121; 40S_S4_C; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR   PROSITE; PS50889; S4; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..263
FT                   /note="40S ribosomal protein S4"
FT                   /id="PRO_0000130826"
FT   DOMAIN          42..104
FT                   /note="S4 RNA-binding"
FT   CONFLICT        116
FT                   /note="S -> A (in Ref. 1; AAH70591)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   263 AA;  29665 MW;  9AA3A805BB8146AB CRC64;
     MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE
     VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR LVYDTKGRFA VHRITSEEAK
     YKLCKVRKTW VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL
     CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNNFAT RLSNIFVIGK GNKPWISLPR
     GKGIRLTIAE ERDKRLAAKQ SSG