ID   RS4_XENTR               Reviewed;         263 AA.
AC   Q6PBC4; Q28HL4;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=40S ribosomal protein S4;
GN   Name=rps4; Synonyms=rps4x; ORFNames=TTpA012h08.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tadpole;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Tadpole;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS4 family.
CC       {ECO:0000305}.
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DR   EMBL; CR760832; CAJ83152.1; -; mRNA.
DR   EMBL; BC059771; AAH59771.1; -; mRNA.
DR   EMBL; BC077671; AAH77671.1; -; mRNA.
DR   RefSeq; NP_988912.1; NM_203581.3.
DR   RefSeq; XP_012823602.1; XM_012968148.1.
DR   AlphaFoldDB; Q6PBC4; -.
DR   SMR; Q6PBC4; -.
DR   IntAct; Q6PBC4; 2.
DR   MINT; Q6PBC4; -.
DR   STRING; 8364.ENSXETP00000056755; -.
DR   PaxDb; Q6PBC4; -.
DR   DNASU; 394507; -.
DR   Ensembl; ENSXETT00000056755; ENSXETP00000056755; ENSXETG00000027073.
DR   Ensembl; ENSXETT00000105051; ENSXETP00000066377; ENSXETG00000027073.
DR   GeneID; 394507; -.
DR   KEGG; xtr:394507; -.
DR   CTD; 6191; -.
DR   Xenbase; XB-GENE-967201; rps4x.
DR   eggNOG; KOG0378; Eukaryota.
DR   HOGENOM; CLU_060400_1_0_1; -.
DR   InParanoid; Q6PBC4; -.
DR   OMA; FPVGLMD; -.
DR   PhylomeDB; Q6PBC4; -.
DR   TreeFam; TF300612; -.
DR   Reactome; R-XTR-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-XTR-72649; Translation initiation complex formation.
DR   Reactome; R-XTR-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-XTR-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-XTR-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027073; Expressed in skeletal muscle tissue and 32 other tissues.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd06087; KOW_RPS4; 1.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 2.40.50.740; -; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   HAMAP; MF_00485; Ribosomal_S4e; 1.
DR   InterPro; IPR032277; 40S_S4_C.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041982; KOW_RPS4.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR000876; Ribosomal_S4e.
DR   InterPro; IPR013845; Ribosomal_S4e_central_region.
DR   InterPro; IPR038237; Ribosomal_S4e_central_sf.
DR   InterPro; IPR013843; Ribosomal_S4e_N.
DR   InterPro; IPR018199; Ribosomal_S4e_N_CS.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   PANTHER; PTHR11581; PTHR11581; 1.
DR   Pfam; PF16121; 40S_S4_C; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF00900; Ribosomal_S4e; 1.
DR   Pfam; PF08071; RS4NT; 1.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF002116; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS00528; RIBOSOMAL_S4E; 1.
DR   PROSITE; PS50889; S4; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..263
FT                   /note="40S ribosomal protein S4"
FT                   /id="PRO_0000130827"
FT   DOMAIN          42..104
FT                   /note="S4 RNA-binding"
SQ   SEQUENCE   263 AA;  29622 MW;  A1C9B93A9B4D5CC1 CRC64;
     MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE
     VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR LVYDTKGRFA VHRITAEEAK
     YKLCKVRKTW VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL
     CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR
     GKGIRLTIAE ERDKRLAAKQ SSG