RS5_MYCS2
ID RS5_MYCS2 Reviewed; 214 AA.
AC A0QSG6; I7G5Q3;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=30S ribosomal protein S5 {ECO:0000255|HAMAP-Rule:MF_01307};
GN Name=rpsE {ECO:0000255|HAMAP-Rule:MF_01307};
GN OrderedLocusNames=MSMEG_1472, MSMEI_1436;
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT mutations or sequencing errors?";
RL Genome Biol. 8:R20.1-R20.9(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS], AND CLEAVAGE OF INITIATOR METHIONINE.
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=18955433; DOI=10.1101/gr.081901.108;
RA Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT and a new MS-based protocol.";
RL Genome Res. 19:128-135(2009).
CC -!- FUNCTION: With S4 and S12 plays an important role in translational
CC accuracy. {ECO:0000255|HAMAP-Rule:MF_01307}.
CC -!- FUNCTION: Located at the back of the 30S subunit body where it
CC stabilizes the conformation of the head with respect to the body.
CC {ECO:0000255|HAMAP-Rule:MF_01307}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S4 and
CC S8. {ECO:0000255|HAMAP-Rule:MF_01307}.
CC -!- DOMAIN: The N-terminal domain interacts with the head of the 30S
CC subunit; the C-terminal domain interacts with the body and contacts
CC protein S4. The interaction surface between S4 and S5 is involved in
CC control of translational fidelity.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS5 family.
CC {ECO:0000255|HAMAP-Rule:MF_01307}.
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DR EMBL; CP000480; ABK71824.1; -; Genomic_DNA.
DR EMBL; CP001663; AFP37909.1; -; Genomic_DNA.
DR RefSeq; WP_003892859.1; NZ_SIJM01000016.1.
DR RefSeq; YP_885854.1; NC_008596.1.
DR PDB; 5O5J; EM; 3.45 A; E=1-214.
DR PDB; 5O61; EM; 3.31 A; BE=1-214.
DR PDB; 5XYU; EM; 3.45 A; E=1-214.
DR PDB; 5ZEB; EM; 3.40 A; e=1-214.
DR PDB; 5ZEP; EM; 3.40 A; e=1-214.
DR PDB; 5ZEU; EM; 3.70 A; e=1-214.
DR PDB; 6DZI; EM; 3.46 A; m=35-214.
DR PDB; 6DZK; EM; 3.60 A; E=2-214.
DR PDBsum; 5O5J; -.
DR PDBsum; 5O61; -.
DR PDBsum; 5XYU; -.
DR PDBsum; 5ZEB; -.
DR PDBsum; 5ZEP; -.
DR PDBsum; 5ZEU; -.
DR PDBsum; 6DZI; -.
DR PDBsum; 6DZK; -.
DR AlphaFoldDB; A0QSG6; -.
DR SMR; A0QSG6; -.
DR IntAct; A0QSG6; 2.
DR STRING; 246196.MSMEI_1436; -.
DR PRIDE; A0QSG6; -.
DR EnsemblBacteria; ABK71824; ABK71824; MSMEG_1472.
DR EnsemblBacteria; AFP37909; AFP37909; MSMEI_1436.
DR GeneID; 66732929; -.
DR KEGG; msg:MSMEI_1436; -.
DR KEGG; msm:MSMEG_1472; -.
DR PATRIC; fig|246196.19.peg.1457; -.
DR eggNOG; COG0098; Bacteria.
DR OMA; KRGCGSW; -.
DR OrthoDB; 1505038at2; -.
DR Proteomes; UP000000757; Chromosome.
DR Proteomes; UP000006158; Chromosome.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.230.10; -; 1.
DR HAMAP; MF_01307_B; Ribosomal_S5_B; 1.
DR InterPro; IPR000851; Ribosomal_S5.
DR InterPro; IPR005712; Ribosomal_S5_bac-type.
DR InterPro; IPR005324; Ribosomal_S5_C.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR InterPro; IPR013810; Ribosomal_S5_N.
DR InterPro; IPR018192; Ribosomal_S5_N_CS.
DR PANTHER; PTHR13718; PTHR13718; 1.
DR Pfam; PF00333; Ribosomal_S5; 1.
DR Pfam; PF03719; Ribosomal_S5_C; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR TIGRFAMs; TIGR01021; rpsE_bact; 1.
DR PROSITE; PS00585; RIBOSOMAL_S5; 1.
DR PROSITE; PS50881; S5_DSRBD; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:18955433"
FT CHAIN 2..214
FT /note="30S ribosomal protein S5"
FT /id="PRO_1000086029"
FT DOMAIN 36..99
FT /note="S5 DRBM"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01307"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 38..40
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 44..47
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 51..53
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 56..59
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 62..65
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 67..69
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 71..74
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 77..80
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 81..92
FT /evidence="ECO:0007829|PDB:5XYU"
FT TURN 93..95
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 105..108
FT /evidence="ECO:0007829|PDB:5O5J"
FT STRAND 110..114
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 117..123
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 130..132
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 134..143
FT /evidence="ECO:0007829|PDB:5XYU"
FT STRAND 148..154
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 158..169
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 175..181
FT /evidence="ECO:0007829|PDB:5XYU"
FT HELIX 186..189
FT /evidence="ECO:0007829|PDB:5O5J"
FT HELIX 192..213
FT /evidence="ECO:0007829|PDB:5O5J"
SQ SEQUENCE 214 AA; 21911 MW; 776D6119907F713C CRC64;
MAEQAGAGSA QDNRGGRGRR DDRGGRGRDG GDKSNYIERV VSINRVSKVV KGGRRFSFTA
LVIVGDGKGM VGVGYGKAKE VPAAIAKGVE EARKNFFRVP LIGSTITHPV QGEAAAGVVM
LRPASPGTGV IAGGAARAVL ECAGVHDILA KSLGSDNAIN VVHATVAALK LLQRPEEVAA
RRGLPIEDVA PAGMLKARRE SEALAAAAAR EGSA
