RS5_PYRFU
ID RS5_PYRFU Reviewed; 236 AA.
AC Q8U017; Q9HH79;
DT 06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=30S ribosomal protein S5 {ECO:0000255|HAMAP-Rule:MF_01307};
DE AltName: Full=PfS5;
DE AltName: Full=Small ribosomal subunit protein uS5;
GN Name=rps5 {ECO:0000255|HAMAP-Rule:MF_01307}; OrderedLocusNames=PF1804;
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=11119702; DOI=10.1016/s0014-5793(00)02293-6;
RA Furumoto H., Taguchi A., Itoh T., Morinaga T., Itoh T.;
RT "5S rRNA binding proteins from the hyperthermophilic archaeon, Pyrococcus
RT furiosus.";
RL FEBS Lett. 486:195-199(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
RN [3] {ECO:0007744|PDB:4V6U}
RP STRUCTURE BY ELECTRON MICROSCOPY (6.60 ANGSTROMS) IN THE 70S RIBOSOME, AND
RP SUBUNIT.
RX PubMed=23222135; DOI=10.1093/nar/gks1259;
RA Armache J.P., Anger A.M., Marquez V., Franckenberg S., Frohlich T.,
RA Villa E., Berninghausen O., Thomm M., Arnold G.J., Beckmann R.,
RA Wilson D.N.;
RT "Promiscuous behaviour of archaeal ribosomal proteins: implications for
RT eukaryotic ribosome evolution.";
RL Nucleic Acids Res. 41:1284-1293(2013).
CC -!- FUNCTION: With S4 and S12 plays an important role in translational
CC accuracy. {ECO:0000255|HAMAP-Rule:MF_01307}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit (PubMed:23222135). Contacts
CC protein S4 (By similarity). {ECO:0000255|HAMAP-Rule:MF_01307,
CC ECO:0000269|PubMed:23222135}.
CC -!- DOMAIN: The N-terminal domain interacts with the head of the 30S
CC subunit; the C-terminal domain interacts with the body and contacts
CC protein S4. The interaction surface between S4 and S5 is involved in
CC control of translational fidelity.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS5 family.
CC {ECO:0000255|HAMAP-Rule:MF_01307}.
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DR EMBL; AB040118; BAB13704.1; -; Genomic_DNA.
DR EMBL; AE009950; AAL81928.1; -; Genomic_DNA.
DR RefSeq; WP_011012945.1; NZ_CP023154.1.
DR PDB; 4V6U; EM; 6.60 A; AF=1-236.
DR PDB; 5JB3; EM; 5.34 A; F=1-236.
DR PDB; 5JBH; EM; 5.34 A; F=1-236.
DR PDBsum; 4V6U; -.
DR PDBsum; 5JB3; -.
DR PDBsum; 5JBH; -.
DR AlphaFoldDB; Q8U017; -.
DR SMR; Q8U017; -.
DR STRING; 186497.PF1804; -.
DR EnsemblBacteria; AAL81928; AAL81928; PF1804.
DR GeneID; 41713623; -.
DR KEGG; pfu:PF1804; -.
DR PATRIC; fig|186497.12.peg.1875; -.
DR eggNOG; arCOG04087; Archaea.
DR HOGENOM; CLU_065898_0_1_2; -.
DR OMA; KRGCGSW; -.
DR OrthoDB; 60954at2157; -.
DR PhylomeDB; Q8U017; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.230.10; -; 1.
DR HAMAP; MF_01307_A; Ribosomal_S5_A; 1.
DR InterPro; IPR000851; Ribosomal_S5.
DR InterPro; IPR005324; Ribosomal_S5_C.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR InterPro; IPR005711; Ribosomal_S5_euk/arc.
DR InterPro; IPR013810; Ribosomal_S5_N.
DR InterPro; IPR018192; Ribosomal_S5_N_CS.
DR PANTHER; PTHR13718; PTHR13718; 1.
DR Pfam; PF00333; Ribosomal_S5; 1.
DR Pfam; PF03719; Ribosomal_S5_C; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR TIGRFAMs; TIGR01020; uS5_euk_arch; 1.
DR PROSITE; PS00585; RIBOSOMAL_S5; 1.
DR PROSITE; PS50881; S5_DSRBD; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..236
FT /note="30S ribosomal protein S5"
FT /id="PRO_0000131657"
FT DOMAIN 61..124
FT /note="S5 DRBM"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01307"
FT CONFLICT 69..128
FT /note="Missing (in Ref. 1; BAB13704)"
FT /evidence="ECO:0000305"
FT CONFLICT 221
FT /note="Y -> S (in Ref. 1; BAB13704)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 236 AA; 26551 MW; 57BBC765DF6EC9CA CRC64;
MSQEWKEYAK RVLDEWEPKT KLGMMVKEGQ ITDIHEIFRR GYQIKEPEII DVLLPEVNAR
ENQEVLDIAL TVRMTDSGRR VRFRVLAAVG NRDGYVGLGI GHGKEVGIAI RKAINYAKLN
IIEIKRGCGS WECRCRRPHS VPFAVEGKEG SVRVRLIPGP RGLGLVIGDV GKKILRLAGV
QDVWSQTFGE TRTTVNFAKA VFNALYNTNR VAISPEMIER YGIVVGRAMP TTFTLE
