BAME_PSEAE
ID BAME_PSEAE Reviewed; 176 AA.
AC O68562;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Outer membrane protein assembly factor BamE {ECO:0000255|HAMAP-Rule:MF_00925};
DE Flags: Precursor;
GN Name=bamE {ECO:0000255|HAMAP-Rule:MF_00925}; Synonyms=omlA, oprX;
GN OrderedLocusNames=PA4765;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=9973334; DOI=10.1128/jb.181.4.1099-1109.1999;
RA Ochsner U.A., Vasil A.I., Johnson Z., Vasil M.L.;
RT "Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer
RT membrane lipoprotein, OmlA.";
RL J. Bacteriol. 181:1099-1109(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane (By similarity). May have a structural role in
CC maintaining the cell envelope integrity. {ECO:0000255|HAMAP-
CC Rule:MF_00925, ECO:0000269|PubMed:9973334}.
CC -!- SUBUNIT: Part of the Bam complex. {ECO:0000255|HAMAP-Rule:MF_00925}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC -!- SIMILARITY: Belongs to the BamE family. {ECO:0000255|HAMAP-
CC Rule:MF_00925}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF050676; AAC05678.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG08151.1; -; Genomic_DNA.
DR PIR; A83050; A83050.
DR RefSeq; NP_253453.1; NC_002516.2.
DR RefSeq; WP_003113904.1; NZ_QZGE01000018.1.
DR PDB; 7JRK; X-ray; 1.71 A; A/B=23-176.
DR PDBsum; 7JRK; -.
DR AlphaFoldDB; O68562; -.
DR SMR; O68562; -.
DR STRING; 287.DR97_2109; -.
DR PaxDb; O68562; -.
DR PRIDE; O68562; -.
DR EnsemblBacteria; AAG08151; AAG08151; PA4765.
DR GeneID; 881781; -.
DR KEGG; pae:PA4765; -.
DR PATRIC; fig|208964.12.peg.4992; -.
DR PseudoCAP; PA4765; -.
DR HOGENOM; CLU_083835_2_1_6; -.
DR InParanoid; O68562; -.
DR OMA; LLTDTFH; -.
DR PhylomeDB; O68562; -.
DR BioCyc; PAER208964:G1FZ6-4878-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:1990063; C:Bam protein complex; IBA:GO_Central.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IBA:GO_Central.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IBA:GO_Central.
DR GO; GO:0051205; P:protein insertion into membrane; IBA:GO_Central.
DR Gene3D; 3.30.1450.10; -; 1.
DR HAMAP; MF_00925; OM_assembly_BamE; 1.
DR InterPro; IPR026592; BamE.
DR InterPro; IPR037873; BamE-like.
DR InterPro; IPR007450; Lipoprotein_SmpA/OmlA.
DR PANTHER; PTHR37482; PTHR37482; 1.
DR Pfam; PF04355; SmpA_OmlA; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT CHAIN 22..176
FT /note="Outer membrane protein assembly factor BamE"
FT /id="PRO_0000032815"
FT REGION 121..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 22
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00925"
FT LIPID 22
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00925"
FT HELIX 40..44
FT /evidence="ECO:0007829|PDB:7JRK"
FT HELIX 52..59
FT /evidence="ECO:0007829|PDB:7JRK"
FT STRAND 63..80
FT /evidence="ECO:0007829|PDB:7JRK"
FT HELIX 85..87
FT /evidence="ECO:0007829|PDB:7JRK"
FT STRAND 89..95
FT /evidence="ECO:0007829|PDB:7JRK"
FT STRAND 99..106
FT /evidence="ECO:0007829|PDB:7JRK"
SQ SEQUENCE 176 AA; 19395 MW; 254A64F50735B1EB CRC64;
MQNAKLMLTC LAFAGLAALA GCSFPGVYKI DIQQGNVVTQ DMIDQLRPGM TRRQVRFIMG
NPLIVDTFHA NRWDYLYSIQ PGGGRRQQER VSLFFNDSDQ LAGLNGDFMP GVSRDEAILG
KEGSTTVTQP ADQQKPEAQK EEPPKPGSTL EQLQREVDEA QPVPVPTPEP LDPSPQ
