RS5_THETH
ID RS5_THETH Reviewed; 162 AA.
AC P27152;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 4.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=30S ribosomal protein S5;
GN Name=rpsE; Synonyms=rps5;
OS Thermus thermophilus.
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=274;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=VK1;
RX PubMed=9249063; DOI=10.1016/s0378-1119(97)00072-3;
RA Vysotskaya V.S., Shcherbakov D.V., Garber M.B.;
RT "Sequencing and analysis of the Thermus thermophilus ribosomal protein gene
RT cluster equivalent to the spectinomycin operon.";
RL Gene 193:23-30(1997).
RN [2]
RP PROTEIN SEQUENCE OF 2-26.
RC STRAIN=VK1;
RX PubMed=1637860; DOI=10.1016/0300-9084(92)90110-z;
RA Garber M.B., Agalarov S.C., Eliseikina I.A., Fomenkova N.P., Nikonov S.V.,
RA Sedelnikova S.E., Shikaeva O.S., Vasiliev D., Zhdanov A.S., Liljas A.,
RA Svensson L.A.;
RT "Ribosomal proteins from Thermus thermophilus for structural
RT investigations.";
RL Biochimie 74:327-336(1992).
CC -!- FUNCTION: With S4 and S12 plays an important role in translational
CC accuracy. {ECO:0000250}.
CC -!- FUNCTION: Located at the back of the 30S subunit body where it
CC stabilizes the conformation of the head with respect to the body.
CC {ECO:0000250}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8
CC (By similarity). {ECO:0000250}.
CC -!- DOMAIN: The N-terminal domain interacts with the head of the 30S
CC subunit; the C-terminal domain interacts with the body and contacts
CC protein S4. The interaction surface between S4 and S5 is involved in
CC control of translational fidelity.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS5 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X90765; CAA62290.1; -; Genomic_DNA.
DR PIR; A48401; A48401.
DR RefSeq; WP_008633389.1; NZ_VHHQ01000024.1.
DR PDB; 4V8X; X-ray; 3.35 A; AE/CE=1-162.
DR PDBsum; 4V8X; -.
DR AlphaFoldDB; P27152; -.
DR SMR; P27152; -.
DR GeneID; 3169827; -.
DR OMA; KRGCGSW; -.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.230.10; -; 1.
DR HAMAP; MF_01307_B; Ribosomal_S5_B; 1.
DR InterPro; IPR000851; Ribosomal_S5.
DR InterPro; IPR005712; Ribosomal_S5_bac-type.
DR InterPro; IPR005324; Ribosomal_S5_C.
DR InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR InterPro; IPR013810; Ribosomal_S5_N.
DR InterPro; IPR018192; Ribosomal_S5_N_CS.
DR PANTHER; PTHR13718; PTHR13718; 1.
DR Pfam; PF00333; Ribosomal_S5; 1.
DR Pfam; PF03719; Ribosomal_S5_C; 1.
DR SUPFAM; SSF54211; SSF54211; 1.
DR TIGRFAMs; TIGR01021; rpsE_bact; 1.
DR PROSITE; PS00585; RIBOSOMAL_S5; 1.
DR PROSITE; PS50881; S5_DSRBD; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; rRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:1637860"
FT CHAIN 2..162
FT /note="30S ribosomal protein S5"
FT /id="PRO_0000131622"
FT DOMAIN 6..69
FT /note="S5 DRBM"
FT CONFLICT 2
FT /note="P -> D (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 5
FT /note="D -> F (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 24
FT /note="R -> V (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT STRAND 9..20
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 23..35
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 37..50
FT /evidence="ECO:0007829|PDB:4V8X"
FT HELIX 51..63
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 64..68
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 72..75
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 80..84
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 87..93
FT /evidence="ECO:0007829|PDB:4V8X"
FT HELIX 104..110
FT /evidence="ECO:0007829|PDB:4V8X"
FT TURN 111..114
FT /evidence="ECO:0007829|PDB:4V8X"
FT STRAND 117..124
FT /evidence="ECO:0007829|PDB:4V8X"
FT HELIX 128..139
FT /evidence="ECO:0007829|PDB:4V8X"
FT HELIX 145..151
FT /evidence="ECO:0007829|PDB:4V8X"
SQ SEQUENCE 162 AA; 17557 MW; BE3367CB619E68D2 CRC64;
MPETDFEEKM ILIRRTARMQ AGGRRFRFGA LVVVGDRQGR VGLGFGKAPE VPLAVQKAGY
YARRNMVEVP LQNGTIPHEI EVEFGASKIV LKPAAPGTGV IAGAVPRAIL ELAGVTDILT
KELGSRNPIN IAYATMEALR QLRTKADVER LRKGEAHAQA QG