ID   RS6_APLCA               Reviewed;         247 AA.
AC   Q9BMX5;
DT   19-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=40S ribosomal protein S6;
GN   Name=RPS6;
OS   Aplysia californica (California sea hare).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Tectipleura; Aplysiida; Aplysioidea;
OC   Aplysiidae; Aplysia.
OX   NCBI_TaxID=6500;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11160419; DOI=10.1523/jneurosci.21-02-00382.2001;
RA   Khan A., Pepio A.M., Sossin W.S.;
RT   "Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia
RT   synaptosomes.";
RL   J. Neurosci. 21:382-391(2001).
CC   -!- FUNCTION: Component of the 40S small ribosomal subunit (By similarity).
CC       Plays an important role in controlling cell growth and proliferation
CC       through the selective translation of particular classes of mRNA (By
CC       similarity). {ECO:0000250|UniProtKB:P62753}.
CC   -!- PTM: Ribosomal protein S6 is the major substrate of protein kinases in
CC       eukaryote ribosomes. {ECO:0000250|UniProtKB:P62753}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS6 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF294917; AAG60623.1; -; mRNA.
DR   RefSeq; NP_001191465.1; NM_001204536.1.
DR   AlphaFoldDB; Q9BMX5; -.
DR   SMR; Q9BMX5; -.
DR   PRIDE; Q9BMX5; -.
DR   GeneID; 100533219; -.
DR   OrthoDB; 1326714at2759; -.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR014401; Ribosomal_S6_euk.
DR   InterPro; IPR001377; Ribosomal_S6e.
DR   InterPro; IPR018282; Ribosomal_S6e_CS.
DR   PANTHER; PTHR11502; PTHR11502; 1.
DR   Pfam; PF01092; Ribosomal_S6e; 1.
DR   PIRSF; PIRSF002129; Ribosom_S6_euk; 1.
DR   SMART; SM01405; Ribosomal_S6e; 1.
DR   PROSITE; PS00578; RIBOSOMAL_S6E; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..247
FT                   /note="40S ribosomal protein S6"
FT                   /id="PRO_0000137319"
FT   REGION          194..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..247
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   247 AA;  28527 MW;  05A7D5B2FA5CBD1F CRC64;
     MKLNISYPAT GCQKLIEVDD EKKLRPFYDK RISAELSADC LGDEWKGYVV RISGGNDKQG
     FPMKQGVLTA TRVRLLLDKN HSCYRPRRTG ERKRKSVRGC IVDSNLSVLS LVIIKKGEQD
     IPGLTDKTIP RRLGPKRASK IRKLFNLSKE DDVRQYVVRR PLPERDGKKA KSKAPKIQRL
     VTPVVLQRKR ARMALKKKRV TKKREDHAEY TKLLAQRMKE AKERKMERKR SNSRSKGDSI
     RESTSKK