ID   RS6_BACSU               Reviewed;          95 AA.
AC   P21468;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 2.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=30S ribosomal protein S6;
DE   AltName: Full=BS9;
GN   Name=rpsF; OrderedLocusNames=BSU40910;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA   Ogasawara N., Nakai S., Yoshikawa H.;
RT   "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT   chromosome containing the replication origin.";
RL   DNA Res. 1:1-14(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   PROTEIN SEQUENCE OF 1-16.
RX   PubMed=6806564; DOI=10.1007/bf00330792;
RA   Higo K., Otaka E., Osawa S.;
RT   "Purification and characterization of 30S ribosomal proteins from Bacillus
RT   subtilis: correlation to Escherichia coli 30S proteins.";
RL   Mol. Gen. Genet. 185:239-244(1982).
RN   [4]
RP   PROTEIN SEQUENCE OF 1-23.
RC   STRAIN=168 / JH642;
RX   PubMed=8755892; DOI=10.1128/jb.178.15.4611-4619.1996;
RA   Graumann P., Schroeder K., Schmid R., Marahiel M.A.;
RT   "Cold shock stress-induced proteins in Bacillus subtilis.";
RL   J. Bacteriol. 178:4611-4619(1996).
RN   [5]
RP   INDUCTION.
RC   STRAIN=168;
RX   PubMed=14762004; DOI=10.1128/jb.186.4.1097-1105.2004;
RA   Lindner C., Nijland R., van Hartskamp M., Bron S., Hamoen L.W.,
RA   Kuipers O.P.;
RT   "Differential expression of two paralogous genes of Bacillus subtilis
RT   encoding single-stranded DNA binding protein.";
RL   J. Bacteriol. 186:1097-1105(2004).
RN   [6] {ECO:0007744|PDB:6HA1, ECO:0007744|PDB:6HA8}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.10 ANGSTROMS) OF 1-95 WITH AND WITHOUT
RP   VIRGINIAMYCIN M, AND SUBUNIT.
RX   PubMed=30126986; DOI=10.1073/pnas.1808535115;
RA   Crowe-McAuliffe C., Graf M., Huter P., Takada H., Abdelshahid M.,
RA   Novacek J., Murina V., Atkinson G.C., Hauryliuk V., Wilson D.N.;
RT   "Structural basis for antibiotic resistance mediated by the Bacillus
RT   subtilis ABCF ATPase VmlR.";
RL   Proc. Natl. Acad. Sci. U.S.A. 115:8978-8983(2018).
CC   -!- FUNCTION: Binds together with S18 to 16S ribosomal RNA. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit.
CC       {ECO:0000269|PubMed:30126986}.
CC   -!- INDUCTION: Strongly expressed during exponential growth, decreases 2-4-
CC       fold in stationary phase, part of the rpsF-ssbA-rpsR operon
CC       (PubMed:14762004). The operon is induced by DNA damage by mitomycin C
CC       (PubMed:14762004). {ECO:0000269|PubMed:14762004}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS6 family.
CC       {ECO:0000305}.
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DR   EMBL; D26185; BAA05221.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB16128.1; -; Genomic_DNA.
DR   PIR; S66015; S66015.
DR   RefSeq; NP_391971.1; NC_000964.3.
DR   RefSeq; WP_003244064.1; NZ_JNCM01000034.1.
DR   PDB; 3J9W; EM; 3.90 A; AF=1-95.
DR   PDB; 5NJT; EM; 3.80 A; F=1-95.
DR   PDB; 6HA1; EM; 3.10 A; f=1-95.
DR   PDB; 6HA8; EM; 3.50 A; f=1-95.
DR   PDB; 6HTQ; EM; 4.50 A; f=3-94.
DR   PDB; 7O5B; EM; 3.33 A; F=1-95.
DR   PDB; 7QV1; EM; 3.50 A; f=1-95.
DR   PDB; 7QV2; EM; 3.50 A; f=1-95.
DR   PDB; 7QV3; EM; 5.14 A; f=1-95.
DR   PDBsum; 3J9W; -.
DR   PDBsum; 5NJT; -.
DR   PDBsum; 6HA1; -.
DR   PDBsum; 6HA8; -.
DR   PDBsum; 6HTQ; -.
DR   PDBsum; 7O5B; -.
DR   PDBsum; 7QV1; -.
DR   PDBsum; 7QV2; -.
DR   PDBsum; 7QV3; -.
DR   AlphaFoldDB; P21468; -.
DR   SMR; P21468; -.
DR   STRING; 224308.BSU40910; -.
DR   jPOST; P21468; -.
DR   PaxDb; P21468; -.
DR   PRIDE; P21468; -.
DR   EnsemblBacteria; CAB16128; CAB16128; BSU_40910.
DR   GeneID; 937919; -.
DR   KEGG; bsu:BSU40910; -.
DR   PATRIC; fig|224308.179.peg.4432; -.
DR   eggNOG; COG0360; Bacteria.
DR   InParanoid; P21468; -.
DR   OMA; ITEASPM; -.
DR   PhylomeDB; P21468; -.
DR   BioCyc; BSUB:BSU40910-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00473; bS6; 1.
DR   Gene3D; 3.30.70.60; -; 1.
DR   HAMAP; MF_00360; Ribosomal_S6; 1.
DR   InterPro; IPR000529; Ribosomal_S6.
DR   InterPro; IPR020815; Ribosomal_S6_CS.
DR   InterPro; IPR020814; Ribosomal_S6_plastid/chlpt.
DR   InterPro; IPR035980; Ribosomal_S6_sf.
DR   InterPro; IPR014717; Transl_elong_EF1B/ribosomal_S6.
DR   PANTHER; PTHR21011; PTHR21011; 1.
DR   Pfam; PF01250; Ribosomal_S6; 1.
DR   SUPFAM; SSF54995; SSF54995; 1.
DR   TIGRFAMs; TIGR00166; S6; 1.
DR   PROSITE; PS01048; RIBOSOMAL_S6; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT   CHAIN           1..95
FT                   /note="30S ribosomal protein S6"
FT                   /id="PRO_0000176726"
SQ   SEQUENCE   95 AA;  11125 MW;  B4C204D6BA5594CC CRC64;
     MRKYEVMYII RPNIDEESKK AVIERFNNVL TSNGAEITGT KDWGKRRLAY EINDFRDGFY
     QIVNVQSDAA AVQEFDRLAK ISDDIIRHIV VKEEE