ID   BANP_XENLA              Reviewed;         509 AA.
AC   Q5FWL0;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Protein BANP;
GN   Name=banp;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-binding protein which may repress cyclin D1 transcription
CC       by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac,
CC       H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell
CC       cycle arrest. {ECO:0000250, ECO:0000250|UniProtKB:Q8VBU8}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BANP/SMAR1 family. {ECO:0000305}.
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DR   EMBL; BC089297; AAH89297.1; -; mRNA.
DR   RefSeq; NP_001089263.1; NM_001095794.1.
DR   AlphaFoldDB; Q5FWL0; -.
DR   SMR; Q5FWL0; -.
DR   DNASU; 734310; -.
DR   GeneID; 734310; -.
DR   KEGG; xla:734310; -.
DR   CTD; 734310; -.
DR   Xenbase; XB-GENE-944409; banp.S.
DR   OrthoDB; 1401911at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 734310; Expressed in gastrula and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   InterPro; IPR042343; BANP.
DR   InterPro; IPR018379; BEN_domain.
DR   PANTHER; PTHR16243; PTHR16243; 1.
DR   Pfam; PF10523; BEN; 1.
DR   SMART; SM01025; BEN; 1.
DR   PROSITE; PS51457; BEN; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Chromatin regulator; Coiled coil; DNA-binding; Nucleus;
KW   Reference proteome; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..509
FT                   /note="Protein BANP"
FT                   /id="PRO_0000297913"
FT   DOMAIN          238..334
FT                   /note="BEN"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00784"
FT   REGION          178..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          68..98
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   509 AA;  56213 MW;  8C154364BD0C2654 CRC64;
     MMSGQELAEV VQIAVEDLHS DHHPVELENH EVTEEDLSPT LKRQRIEINC QDPSIKSFLF
     SINQTICLRL DSIESKLQVL EATCKSLEEK LDLIMNKQPN PIQVPMVAGS PLGATQTWNK
     VRCVVPQTTV ILNNERQSTS VTKLEAHEES INRTTETLEN MLNSAVPGRR HNTIVVKVPA
     PEDSHNDDDN DSGSEASDTL SNCGNSSSNM GNNVTLITLN SEEDYPNGTW LGDEHNAEMR
     VRCPITAADM LHISTNCRTA EKMALTLLDY LFHREIQAVS NLSGQGKHGK KQLDPLMIYG
     IRCHLFNKFR ITESDWYRIK QSIDSKCRTA WRRKQRGQSL TVKSFSRRTP SSSSYTTTEG
     VQNTVSSSSD LQQTSPQALH YALANAQQVQ IHQIGEDGQV QVGHLHIAQV PQGEQVQITQ
     DSEGNLQIHQ VHVGQDGQVL QGAQLIAVAS ADPTTGVVDG SPLQANDIQV QYVQLAPVAE
     SSATAQAVEP LQTALQPEMH IEHGAIQIQ