ID   BAP18_BOVIN             Reviewed;         172 AA.
AC   Q32LD1;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Chromatin complexes subunit BAP18;
DE   AltName: Full=BPTF-associated protein of 18 kDa;
GN   Name=BAP18;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of chromatin complexes such as the MLL1/MLL and
CC       NURF complexes. {ECO:0000250}.
CC   -!- SUBUNIT: Component of some MLL1/MLL complex, at least composed of the
CC       core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well
CC       as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1,
CC       LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2,
CC       RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and
CC       TEX10. Component of the nucleosome-remodeling factor (NURF) complex (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; BC109638; AAI09639.1; -; mRNA.
DR   RefSeq; NP_001033181.1; NM_001038092.1.
DR   AlphaFoldDB; Q32LD1; -.
DR   SMR; Q32LD1; -.
DR   STRING; 9913.ENSBTAP00000029238; -.
DR   PaxDb; Q32LD1; -.
DR   PRIDE; Q32LD1; -.
DR   Ensembl; ENSBTAT00000029238; ENSBTAP00000029238; ENSBTAG00000021931.
DR   GeneID; 512885; -.
DR   KEGG; bta:512885; -.
DR   CTD; 115154397; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021931; -.
DR   VGNC; VGNC:107267; C19H17orf49.
DR   eggNOG; KOG4834; Eukaryota.
DR   GeneTree; ENSGT00390000014721; -.
DR   HOGENOM; CLU_104449_0_0_1; -.
DR   InParanoid; Q32LD1; -.
DR   OMA; HESDNND; -.
DR   TreeFam; TF324877; -.
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000021931; Expressed in oocyte and 106 other tissues.
DR   ExpressionAtlas; Q32LD1; baseline and differential.
DR   GO; GO:0071339; C:MLL1 complex; ISS:UniProtKB.
DR   GO; GO:0016589; C:NURF complex; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   CDD; cd00167; SANT; 1.
DR   InterPro; IPR037931; BAP18.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001005; SANT/Myb.
DR   PANTHER; PTHR21397:SF2; PTHR21397:SF2; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   2: Evidence at transcript level;
KW   Chromatin regulator; DNA-binding; Nucleus; Phosphoprotein;
KW   Reference proteome.
FT   CHAIN           1..172
FT                   /note="Chromatin complexes subunit BAP18"
FT                   /id="PRO_0000264250"
FT   DOMAIN          38..86
FT                   /note="SANT"
FT   REGION          87..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..124
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         96
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9DCT6"
SQ   SEQUENCE   172 AA;  17960 MW;  FF0881CCADAAAE5C CRC64;
     MTSASTKVGE IFSAAGAAFT KLGELTMQLH PVADSSPAGA KWTETEIEML RAAVKRFGDD
     LNHISCVIKE RTVAQIKATV KRKVYEDSGI PLPADSPKKG PKKVASGVLS PPPTAPPPSS
     SSVPEAGGPP IKKQKADVTL SALNDSDANS DLVDIEGLGE TPPTKKLNFD QA