RS6_KLULA
ID RS6_KLULA Reviewed; 236 AA.
AC Q6CM04; Q6HA22;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=40S ribosomal protein S6;
GN Name=RPS6; OrderedLocusNames=KLLA0E24090g;
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 18-236.
RX PubMed=15157744; DOI=10.1016/j.bbaexp.2004.03.004;
RA Tarrio N., Diaz Prado S., Cerdan M.E., Gonzales Siso M.I.;
RT "Isolation and characterization of two nuclear genes encoding glutathione
RT and thioredoxin reductases from the yeast Kluyveromyces lactis.";
RL Biochim. Biophys. Acta 1678:170-175(2004).
CC -!- PTM: Phosphorylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS6 family.
CC {ECO:0000305}.
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DR EMBL; CR382125; CAH00122.1; -; Genomic_DNA.
DR EMBL; AJ504414; CAD43214.1; -; Genomic_DNA.
DR RefSeq; XP_455035.1; XM_455035.1.
DR PDB; 3J80; EM; 3.75 A; G=1-236.
DR PDB; 3J81; EM; 4.00 A; G=1-236.
DR PDB; 3JAM; EM; 3.46 A; G=1-236.
DR PDB; 3JAP; EM; 4.90 A; G=1-236.
DR PDB; 3JAQ; EM; 6.00 A; G=1-236.
DR PDB; 5IT7; EM; 3.60 A; G=1-226.
DR PDB; 5IT9; EM; 3.80 A; G=1-226.
DR PDB; 6FYX; EM; 3.05 A; G=1-236.
DR PDB; 6FYY; EM; 3.05 A; G=1-236.
DR PDB; 6GSM; EM; 5.15 A; G=1-226.
DR PDB; 6GSN; EM; 5.75 A; G=1-226.
DR PDB; 6UZ7; EM; 3.60 A; G=1-236.
DR PDBsum; 3J80; -.
DR PDBsum; 3J81; -.
DR PDBsum; 3JAM; -.
DR PDBsum; 3JAP; -.
DR PDBsum; 3JAQ; -.
DR PDBsum; 5IT7; -.
DR PDBsum; 5IT9; -.
DR PDBsum; 6FYX; -.
DR PDBsum; 6FYY; -.
DR PDBsum; 6GSM; -.
DR PDBsum; 6GSN; -.
DR PDBsum; 6UZ7; -.
DR AlphaFoldDB; Q6CM04; -.
DR SMR; Q6CM04; -.
DR STRING; 28985.XP_455035.1; -.
DR EnsemblFungi; CAH00122; CAH00122; KLLA0_E24047g.
DR GeneID; 2894345; -.
DR KEGG; kla:KLLA0_E24047g; -.
DR eggNOG; KOG1646; Eukaryota.
DR HOGENOM; CLU_046346_0_1_1; -.
DR InParanoid; Q6CM04; -.
DR OMA; FYEKRMS; -.
DR Proteomes; UP000000598; Chromosome E.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR InterPro; IPR014401; Ribosomal_S6_euk.
DR InterPro; IPR001377; Ribosomal_S6e.
DR InterPro; IPR018282; Ribosomal_S6e_CS.
DR PANTHER; PTHR11502; PTHR11502; 1.
DR Pfam; PF01092; Ribosomal_S6e; 1.
DR PIRSF; PIRSF002129; Ribosom_S6_euk; 1.
DR SMART; SM01405; Ribosomal_S6e; 1.
DR PROSITE; PS00578; RIBOSOMAL_S6E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1..236
FT /note="40S ribosomal protein S6"
FT /id="PRO_0000137337"
FT MOD_RES 232
FT /note="Phosphoserine"
FT /evidence="ECO:0000255"
FT MOD_RES 233
FT /note="Phosphoserine"
FT /evidence="ECO:0000255"
FT STRAND 2..7
FT /evidence="ECO:0007829|PDB:3JAM"
FT TURN 8..11
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 12..17
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 21..24
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 25..27
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 34..38
FT /evidence="ECO:0007829|PDB:3JAM"
FT TURN 39..41
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 49..60
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 69..71
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 73..77
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 79..83
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 93..98
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 104..115
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 124..126
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 138..145
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 154..156
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 160..166
FT /evidence="ECO:0007829|PDB:3JAM"
FT STRAND 168..171
FT /evidence="ECO:0007829|PDB:3JAM"
FT HELIX 181..222
FT /evidence="ECO:0007829|PDB:3JAM"
SQ SEQUENCE 236 AA; 26912 MW; BC919D228C9CF77B CRC64;
MKLNISYPIN GTQKCIEIDD EHRVRVFYDK RIGQEVDGES VGDEFKGYVF KIAGGNDKQG
FPMKQGVLLP TRVKLLLAKG HSCYRPRRNG ERKRKSVRGA IVGPDLAVLA LIITKKGEQE
IEGITNDTVP KRLGPKRANN IRKFFGLTKE DDVRDYVIRR EVTKGDKSYT KAPKIQRLVT
PQRLQRKRQQ KSLKIKNAQA QREAAAEYAQ LLAKRLSERK AEKAEVRKRR ASSLKA
