ID   RS6_MANSE               Reviewed;         253 AA.
AC   Q94624;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=40S ribosomal protein S6;
GN   Name=RpS6;
OS   Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Sphingidae; Sphinginae; Sphingini; Manduca.
OX   NCBI_TaxID=7130;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Prothoracic gland;
RX   PubMed=9020166; DOI=10.1074/jbc.272.7.4429;
RA   Song Q., Gilbert L.I.;
RT   "Molecular cloning, developmental expression, and phosphorylation of
RT   ribosomal protein S6 in the endocrine gland responsible for insect
RT   molting.";
RL   J. Biol. Chem. 272:4429-4435(1997).
CC   -!- FUNCTION: Component of the 40S small ribosomal subunit (By similarity).
CC       Plays an important role in controlling cell growth and proliferation
CC       through the selective translation of particular classes of mRNA (By
CC       similarity). {ECO:0000250|UniProtKB:P62753}.
CC   -!- PTM: Ribosomal protein S6 is the major substrate of protein kinases in
CC       eukaryote ribosomes. {ECO:0000250|UniProtKB:P62753}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS6 family.
CC       {ECO:0000305}.
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DR   EMBL; U64795; AAB06459.1; -; mRNA.
DR   AlphaFoldDB; Q94624; -.
DR   SMR; Q94624; -.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR014401; Ribosomal_S6_euk.
DR   InterPro; IPR001377; Ribosomal_S6e.
DR   InterPro; IPR018282; Ribosomal_S6e_CS.
DR   PANTHER; PTHR11502; PTHR11502; 1.
DR   Pfam; PF01092; Ribosomal_S6e; 1.
DR   PIRSF; PIRSF002129; Ribosom_S6_euk; 1.
DR   SMART; SM01405; Ribosomal_S6e; 1.
DR   PROSITE; PS00578; RIBOSOMAL_S6E; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..253
FT                   /note="40S ribosomal protein S6"
FT                   /id="PRO_0000137324"
FT   REGION          209..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        209..241
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   253 AA;  29038 MW;  0E128ED7773C9E13 CRC64;
     MKLNVSFPAT GCQKLFEVVD EHKLRIFYEK RMGAEVEADL LGDEWKGYVL RVAGGNDKQG
     FPMKQGVLTN SRVRLLMSKG HSCYRPRRDG ERKRKSVRGC IVDANLSVLA LVIVRKGEQE
     IPGLTDGNVP RRLGPKRASK IRKLFNLSKE DDVRRYVVKA LLPAKEGKEN AKPRYKAPKI
     QRLVTPVVLQ RRRHRLALKK KRLAKRKSAE ADYAKLLAQR KKESKVRRQE EIKRRRSASM
     RDSKSSNQSA PQK