ID   BAP29_BOVIN             Reviewed;         240 AA.
AC   Q32KL9;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=B-cell receptor-associated protein 29;
DE            Short=BCR-associated protein 29;
DE            Short=Bap29;
GN   Name=BCAP29;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in anterograde transport of membrane proteins
CC       from the endoplasmic reticulum to the Golgi. May be involved in CASP8-
CC       mediated apoptosis (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer and heterodimer with BCAP31. Binds CASP8 as a
CC       complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with
CC       VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1
CC       and non-muscle myosin II (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BCAP29/BCAP31 family. {ECO:0000305}.
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DR   EMBL; BC110030; AAI10031.1; -; mRNA.
DR   RefSeq; NP_001033164.1; NM_001038075.1.
DR   RefSeq; XP_005205464.1; XM_005205407.3.
DR   RefSeq; XP_005205465.1; XM_005205408.3.
DR   AlphaFoldDB; Q32KL9; -.
DR   SMR; Q32KL9; -.
DR   STRING; 9913.ENSBTAP00000029129; -.
DR   PaxDb; Q32KL9; -.
DR   PRIDE; Q32KL9; -.
DR   Ensembl; ENSBTAT00000029129; ENSBTAP00000029129; ENSBTAG00000021849.
DR   GeneID; 511018; -.
DR   KEGG; bta:511018; -.
DR   CTD; 55973; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021849; -.
DR   VGNC; VGNC:28247; DUS4L.
DR   eggNOG; KOG1962; Eukaryota.
DR   GeneTree; ENSGT00550000074907; -.
DR   HOGENOM; CLU_070975_1_0_1; -.
DR   InParanoid; Q32KL9; -.
DR   OrthoDB; 1514108at2759; -.
DR   TreeFam; TF315310; -.
DR   Proteomes; UP000009136; Chromosome 4.
DR   Bgee; ENSBTAG00000021849; Expressed in spermatid and 104 other tissues.
DR   ExpressionAtlas; Q32KL9; baseline.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008417; BAP29/BAP31.
DR   InterPro; IPR040463; BAP29/BAP31_N.
DR   InterPro; IPR041672; Bap31/Bap29_C.
DR   PANTHER; PTHR12701; PTHR12701; 1.
DR   Pfam; PF05529; Bap31; 1.
DR   Pfam; PF18035; Bap31_Bap29_C; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Coiled coil; Endoplasmic reticulum; ER-Golgi transport;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..240
FT                   /note="B-cell receptor-associated protein 29"
FT                   /id="PRO_0000327212"
FT   TOPO_DOM        1..6
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..43
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        65..103
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        125..240
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   COILED          166..233
FT                   /evidence="ECO:0000250"
FT   MOTIF           237..240
FT                   /note="Di-lysine motif"
SQ   SEQUENCE   240 AA;  28212 MW;  8A196CF34E742BA3 CRC64;
     MTLQWTAVAT FLYAEIGLIL IFCLPFIPPQ RWQKIFSFSV WGKIASFWNK AFLTIIILLI
     VLFLDAVREV RKYSSTHTIE KSSASRPAAY EHTQMKLFRS QRNLYISGFS LFFWLVLRRL
     VTLITQLAKE LSHKGVLKHQ AENINQAAKK FMEENERLKR LLKNYGKEEE HILEAENKKL
     EEDKEKLKTE LKKASDALSK AQNDVMIMKM QSERLSKEYD RLLREHSELQ DRAGKDKKCL