ID   RS6_ONCMY               Reviewed;         249 AA.
AC   Q9YGF2;
DT   19-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=40S ribosomal protein S6;
GN   Name=rps6;
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Midgut;
RA   Poon K.-H.;
RL   Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the 40S small ribosomal subunit (By similarity).
CC       Plays an important role in controlling cell growth and proliferation
CC       through the selective translation of particular classes of mRNA (By
CC       similarity). {ECO:0000250|UniProtKB:P62753}.
CC   -!- PTM: Ribosomal protein S6 is the major substrate of protein kinases in
CC       eukaryote ribosomes. The phosphorylation is stimulated by growth
CC       factors, tumor promoting agents, and mitogens. It is dephosphorylated
CC       at growth arrest. {ECO:0000250|UniProtKB:P62753}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS6 family.
CC       {ECO:0000305}.
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DR   EMBL; AF009665; AAD01429.1; -; mRNA.
DR   RefSeq; NP_001117716.1; NM_001124244.1.
DR   AlphaFoldDB; Q9YGF2; -.
DR   SMR; Q9YGF2; -.
DR   GeneID; 100135859; -.
DR   KEGG; omy:100135859; -.
DR   OrthoDB; 1326714at2759; -.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; ISS:AgBase.
DR   GO; GO:0005634; C:nucleus; ISS:AgBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:AgBase.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR014401; Ribosomal_S6_euk.
DR   InterPro; IPR001377; Ribosomal_S6e.
DR   InterPro; IPR018282; Ribosomal_S6e_CS.
DR   PANTHER; PTHR11502; PTHR11502; 1.
DR   Pfam; PF01092; Ribosomal_S6e; 1.
DR   PIRSF; PIRSF002129; Ribosom_S6_euk; 1.
DR   SMART; SM01405; Ribosomal_S6e; 1.
DR   PROSITE; PS00578; RIBOSOMAL_S6E; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..249
FT                   /note="40S ribosomal protein S6"
FT                   /id="PRO_0000137317"
FT   REGION          216..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..233
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         235
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         236
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         240
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         244
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         247
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   249 AA;  28682 MW;  84F0F3B3FE6233F4 CRC64;
     MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADP LGDEWKGYMV RISGGNDKQG
     FPMKQGVLTH GRVRLLLAKG HSCYRPRRTG ERKRKSVRGC IGDANLSVLN LVIIKKGEKD
     IPGLTDSTVP RRLGPKRASK IRKLFNLAKE DDVRQYVVRR PLTKEGKKPR TKAPRIQRLV
     TPRVLQHKRR RIALKKQRTQ KNKEEASEYA KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS
     TSKSESSQK