ABCB7_DICDI
ID ABCB7_DICDI Reviewed; 824 AA.
AC Q55DA7;
DT 09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=ABC transporter B family member 7;
DE AltName: Full=ABC transporter ABCB.7;
GN Name=abcB7; ORFNames=DDB_G0269720;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255|PROSITE-ProRule:PRU00441};
CC Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCB family.
CC {ECO:0000305}.
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DR EMBL; AAFI02000005; EAL72210.1; -; Genomic_DNA.
DR RefSeq; XP_646224.1; XM_641132.1.
DR AlphaFoldDB; Q55DA7; -.
DR SMR; Q55DA7; -.
DR STRING; 44689.DDB0220443; -.
DR PaxDb; Q55DA7; -.
DR PRIDE; Q55DA7; -.
DR EnsemblProtists; EAL72210; EAL72210; DDB_G0269720.
DR GeneID; 8617178; -.
DR KEGG; ddi:DDB_G0269720; -.
DR dictyBase; DDB_G0269720; abcB7.
DR eggNOG; KOG0058; Eukaryota.
DR HOGENOM; CLU_343695_0_0_1; -.
DR InParanoid; Q55DA7; -.
DR OMA; FIYIWRF; -.
DR PhylomeDB; Q55DA7; -.
DR PRO; PR:Q55DA7; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006935; P:chemotaxis; IMP:dictyBase.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; PTHR24221; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..824
FT /note="ABC transporter B family member 7"
FT /id="PRO_0000391328"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 347..367
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 167..489
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 521..767
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT REGION 41..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 570..576
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 824 AA; 93974 MW; 2AA78E4F94ADAD2D CRC64;
MTRKSNYNYL DEDNIEDESP IGLGTSPIEF NLDKENKNKK RNSVKFNLDT PLPIINNKSS
QDNNNKNNNN NNNNNNNNNN NNNNNNNNNN NNKNNKNKIN NSLNSITPYL VDYKDDFDFK
RSVYDFDDVD YLEEDSFDEH SFYKTSYSTR RCIYRILTYI RPQIWYFVFA FLALSITTLC
QLALPYCFAN GIQEAIRVNL TVNSVNSTDN NIIITPTPTP NITTTTTNPT VLESITSKYT
SLFGNTEYDF KWIIIIVLVQ TPFLFARYLL FTMAGFSVVT KLKRDLFKSL LTQEVSYFDS
NRTGDLKAVI ASDSSILQNC ITVSLSTLVR CSLQLIGGLL ILVFLSWKVT LLMISFLVIL
LISFLVFKKW IHPKYNYIQE KLVNIGLIID DSIGNIKEIR LLNAESKELR SFETELEILH
RSSRSFVLMN AFWISFGSLL VMGTIIGIYG FAMSQTLSNS ILLLQFILYS LMITASMNGL
IGSINEIQKL ISSSKRIFSL IDRKPIVHFQ GGITPSTDSN ISFDNVYFNN NNNNSNNNNN
NNNNNKNNNG MILSNVSFIV NKGQWLSLVG PSQSKEFIFS LIQGLYYPTR GTVFIGRIDT
KVLDLYFFRS RLFTISPLQT VIFDGTVEQN IRYGLSHLST QNIIDASKKA NLHDFVIGLP
HGYDSMIGKN NFFDPIQILK ISIARAFLRN PSVLLLDETT LPFDSKEIED SIELLVQNKT
VIAIANKLST LKRSNNILVF DDNRIIERGT HSELSQKSTS FYVTSVLNSI NNKYNNNNNN
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN INNNNKIEIY LFLI
