BAR1_SCHCO
ID BAR1_SCHCO Reviewed; 639 AA.
AC Q92275; P87022;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1998, sequence version 2.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Pheromone B alpha 1 receptor;
GN Name=BAR1;
OS Schizophyllum commune (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=5334;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1-69;
RX PubMed=8978100; DOI=10.1111/j.1574-6968.1996.tb08615.x;
RA Wendland J., Kothe E.;
RT "Allelic divergence at B alpha 1 pheromone receptor genes of Schizophyllum
RT commune.";
RL FEMS Microbiol. Lett. 145:451-455(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-359.
RC STRAIN=ATCC 44201 / CBS 340.81 / UVM 4-40 / 4-40;
RX PubMed=7489716; DOI=10.1002/j.1460-2075.1995.tb00211.x;
RA Wendland J., Vaillancourt L.J., Hegner J., Lengeler K.B., Laddison K.J.,
RA Specht C.A., Raper C.A., Kothe E.;
RT "The mating-type locus B alpha 1 of Schizophyllum commune contains a
RT pheromone receptor gene and putative pheromone genes.";
RL EMBO J. 14:5271-5278(1995).
CC -!- FUNCTION: Receptor for the BAP1 pheromone, a prenylated mating factor.
CC Has a role in the initiation of B-regulated nuclear migration.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 4 family.
CC {ECO:0000305}.
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DR EMBL; X94996; CAA64453.1; -; Genomic_DNA.
DR EMBL; X77949; CAA54915.1; -; Genomic_DNA.
DR PIR; S61919; S61919.
DR AlphaFoldDB; Q92275; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0004934; F:mating-type alpha-factor pheromone receptor activity; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR InterPro; IPR000481; GPCR_Pheromne_B_alpha_rcpt.
DR InterPro; IPR001499; GPCR_STE3.
DR PANTHER; PTHR28097; PTHR28097; 1.
DR Pfam; PF02076; STE3; 1.
DR PRINTS; PR00899; GPCRSTE3.
DR PRINTS; PR00901; PHEROMONEBAR.
PE 3: Inferred from homology;
KW G-protein coupled receptor; Membrane; Pheromone response; Receptor;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..639
FT /note="Pheromone B alpha 1 receptor"
FT /id="PRO_0000195070"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 375..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 71
FT /note="S -> C (in Ref. 2; CAA54915)"
FT /evidence="ECO:0000305"
FT CONFLICT 109
FT /note="K -> E (in Ref. 2; CAA54915)"
FT /evidence="ECO:0000305"
FT CONFLICT 131
FT /note="Q -> R (in Ref. 2; CAA54915)"
FT /evidence="ECO:0000305"
FT CONFLICT 155
FT /note="P -> A (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 157
FT /note="T -> N (in Ref. 2)"
FT /evidence="ECO:0000305"
FT CONFLICT 177
FT /note="V -> G (in Ref. 2; CAA54915)"
FT /evidence="ECO:0000305"
FT CONFLICT 304
FT /note="R -> K (in Ref. 2; CAA54915)"
FT /evidence="ECO:0000305"
FT CONFLICT 348
FT /note="N -> S (in Ref. 2; CAA54915)"
FT /evidence="ECO:0000305"
FT CONFLICT 358
FT /note="F -> L (in Ref. 2)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 639 AA; 69967 MW; B21A6881579139E0 CRC64;
MLDPLYPLFP IFAFLGFVLA ILPLPWHLQA WNSGTCFFMM WTALGCLNQF INSVAWADDA
MNKAPVWCEI SIRILMGASV GIPASSLCII RRLYYIAKVR AVSKTRAEKM RAILVDALIC
VLFPLVYIAL QYIVQGHRFN ILENIGCYPA VTNTPVTYVV SYVWPVLLGL ISATYGVMAL
LQFNKHRLQF SQFLHTHSTL SASRYLRLMA LALTEMMCTM PLGIFVIVLN SKTENIQPWV
SLAVTHYGFG RIDQVPAIVW RSQHLIVVCN ELTRWCAPVS AFIFFFYFGF AEEARRNYAA
AWRRVCRALG LPERVPSLPT TKKPFSSSDN KGSGFAEKFA AKAKGFSNFN VKDFTSEFTS
KAHDFTSKAK QYTLPRPMPQ TLSSSGFSSS DSTRFGSSVD GKELPSPTTK EFSSPIPIHL
SGMQTLASFD SNKDLPSPPA YDIEAQYGPY NIDNRVSYHI ADTGVRASYP MGVAYSSDSE
HRRIVPHHST VPHHSTADEP ASPALPDTPS SCSSSATFST LQSRDFIVLP SSADVTRRDS
GSSAGGVAST SRPTRAGPPR LPSLSQLFGI SSMRGQEGDV EAQGEEMAAD VDVSEMVLDT
LAPASIIAAT TTAGAPATTT PDRGEPDVPT SPRTHRASV
