BAR3_SCHCM
ID BAR3_SCHCM Reviewed; 626 AA.
AC P56502; D8QF48; O13589; Q6UDE6;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 08-MAR-2011, sequence version 2.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Pheromone B alpha 3 receptor;
GN Name=BAR3; ORFNames=SCHCODRAFT_258340;
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210;
RX PubMed=14643262; DOI=10.1016/j.fgb.2003.08.009;
RA Fowler T.J., Mitton M.F., Rees E.I., Raper C.A.;
RT "Crossing the boundary between the Balpha and Bbeta mating-type loci in
RT Schizophyllum commune.";
RL Fungal Genet. Biol. 41:89-101(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210;
RA Hegner J., Vaillancourt L.J., Raper C.A., Kothe E.;
RT "The determination of specificity in the Balpha receptors of Schizophyllum
RT commune.";
RL Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210;
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- FUNCTION: Receptor for the BAP3 pheromone, a prenylated mating factor.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 4 family.
CC {ECO:0000305}.
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DR EMBL; AY372275; AAR99648.1; -; Genomic_DNA.
DR EMBL; U76688; AAB61998.1; -; Genomic_DNA.
DR EMBL; GL377311; EFI93067.1; -; Genomic_DNA.
DR RefSeq; XP_003027970.1; XM_003027924.1.
DR AlphaFoldDB; P56502; -.
DR STRING; 578458.P56502; -.
DR EnsemblFungi; EFI93067; EFI93067; SCHCODRAFT_258340.
DR GeneID; 9592022; -.
DR KEGG; scm:SCHCODRAFT_258340; -.
DR eggNOG; ENOG502S44N; Eukaryota.
DR HOGENOM; CLU_027592_0_2_1; -.
DR InParanoid; P56502; -.
DR OMA; VFIANIE; -.
DR OrthoDB; 730409at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0004934; F:mating-type alpha-factor pheromone receptor activity; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR InterPro; IPR000481; GPCR_Pheromne_B_alpha_rcpt.
DR InterPro; IPR001499; GPCR_STE3.
DR PANTHER; PTHR28097; PTHR28097; 1.
DR Pfam; PF02076; STE3; 1.
DR PRINTS; PR00899; GPCRSTE3.
DR PRINTS; PR00901; PHEROMONEBAR.
PE 3: Inferred from homology;
KW G-protein coupled receptor; Membrane; Pheromone response; Receptor;
KW Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..626
FT /note="Pheromone B alpha 3 receptor"
FT /id="PRO_0000195072"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 363..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 470
FT /note="S -> R (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 473
FT /note="E -> V (in Ref. 1; AAR99648 and 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 493..497
FT /note="PTSPA -> SDLPF (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 507
FT /note="S -> L (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 586
FT /note="A -> P (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 596
FT /note="T -> S (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 601
FT /note="A -> S (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
FT CONFLICT 606..608
FT /note="ANI -> EY (in Ref. 2; AAB61998)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 626 AA; 68641 MW; D169BB05CFAC656A CRC64;
MLDPTYPLFP TFAFLGFVLA LVPLPWHLQA WNSGTCFFMV WTALGCLNQF VNSIVWKDNA
INSAPIWCEI SIRITMGLSV GLPASSLCII RRLYHIAKVR AVSHTRAEKM RVIIIDALIC
VLFPLVYIAM QYIVQGHRFN ILENVGCYPA VFNTPVTYVV SYIWPVLIGM VSATYSVLAL
IEFNRHRLQF SQFLHSNSTL SVSRYLRLMA LAMTEMCCTV PLGIFVIVLN CTSTPIEPWV
SLKATHYWYS RVDQYPAVVW RSSHLVVVCN ELTRWLAPVS AMLFFAYFGF AQEARRNYAA
AWAWACRALG LPERIATLPT TKSKGPGFAE KFAAKAKGLS SFNVKDFTSE FSSKAHDFTS
KAKQYTLPRP MPQTPSSSGF SSSESTRFGS SVDGKELPSP TTKEFSSPIP IHLSGMQTLV
SFDSNKDLPS PPAYDVEAQY GPYNIDNRVS YHIADAGVRA SYPMGVAYSS DSEHRRINPH
ATFTSANNDT DEPTSPALPD TPSSCSSSAT FSTLQSRDFI VLPSTTDVTR DTGSLPIRRS
PAGPPRLPSL SQLFGISSMR AEGRDVEAQV QDVATGTAAP TTTAPAPAST TIAPATTTAT
APTTTANIQR GEPDVPTSPR THRASV
