BASS1_ARATH
ID BASS1_ARATH Reviewed; 401 AA.
AC Q93YR2; Q9SYM6;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Probable sodium/metabolite cotransporter BASS1, chloroplastic;
DE AltName: Full=Bile acid transporter 2;
DE AltName: Full=Bile acid-sodium symporter family protein 1;
DE Flags: Precursor;
GN Name=BASS1; Synonyms=BAT2; OrderedLocusNames=At1g78560; ORFNames=T30F21.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=19542295; DOI=10.1105/tpc.109.066399;
RA Gigolashvili T., Yatusevich R., Rollwitz I., Humphry M., Gershenzon J.,
RA Fluegge U.-I.;
RT "The plastidic bile acid transporter 5 is required for the biosynthesis of
RT methionine-derived glucosinolates in Arabidopsis thaliana.";
RL Plant Cell 21:1813-1829(2009).
CC -!- FUNCTION: May function as sodium-coupled metabolite transporter across
CC the chloroplast envelope. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305|PubMed:19542295}; Multi-
CC pass membrane protein {ECO:0000305|PubMed:19542295}. Plastid,
CC chloroplast envelope {ECO:0000305|PubMed:19542295}.
CC -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC 2.A.28) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD30581.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007260; AAD30581.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE36121.1; -; Genomic_DNA.
DR EMBL; AY059808; AAL24290.1; -; mRNA.
DR EMBL; BT000024; AAN15343.1; -; mRNA.
DR EMBL; AY088098; AAM65644.1; -; mRNA.
DR PIR; B96814; B96814.
DR RefSeq; NP_565182.1; NM_106503.3.
DR AlphaFoldDB; Q93YR2; -.
DR SMR; Q93YR2; -.
DR STRING; 3702.AT1G78560.1; -.
DR iPTMnet; Q93YR2; -.
DR PaxDb; Q93YR2; -.
DR PRIDE; Q93YR2; -.
DR ProteomicsDB; 240745; -.
DR EnsemblPlants; AT1G78560.1; AT1G78560.1; AT1G78560.
DR GeneID; 844192; -.
DR Gramene; AT1G78560.1; AT1G78560.1; AT1G78560.
DR KEGG; ath:AT1G78560; -.
DR Araport; AT1G78560; -.
DR TAIR; locus:2202935; AT1G78560.
DR eggNOG; KOG2718; Eukaryota.
DR HOGENOM; CLU_034788_1_2_1; -.
DR InParanoid; Q93YR2; -.
DR OMA; VPWIFAF; -.
DR OrthoDB; 1148347at2759; -.
DR PhylomeDB; Q93YR2; -.
DR PRO; PR:Q93YR2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q93YR2; baseline and differential.
DR Genevisible; Q93YR2; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009941; C:chloroplast envelope; IDA:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0098717; P:pantothenate import across plasma membrane; IMP:TAIR.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR004710; Bilac:Na_transpt.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR10361; PTHR10361; 1.
DR Pfam; PF01758; SBF; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..70
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 71..401
FT /note="Probable sodium/metabolite cotransporter BASS1,
FT chloroplastic"
FT /id="PRO_0000418602"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 401 AA; 42747 MW; 4776AE0477104DD6 CRC64;
MASAISLSLL NGATPLKSNS LHKSRLTPLH LRTISCSRLS YSPSSREISL KTQSTVPISC
RRSRFDFVPR CGISSNDLPT EKKKSFGEWV EFVGEAVSTA FPIWVSLGCL LGLMRPSTFN
WVTPNWTIVG LTITMLGMGM TLTLDDLRGA LSMPKELFAG FLLQYSVMPL SAFFVSKLLN
LPPHYAAGLI LVGCCPGGTA SNIVTYIARG NVALSVLMTA ASTVSAVIMT PLLTAKLAKQ
YITVDALGLL MSTLQVVLLP VLAGAFLNQY FKKLVKFVSP VMPPIAVGTV AILCGYAIGQ
NASAILMSGK QVVLASCLLH ISGFLFGYLF SRILGIDVAS SRTISIEVGM QNSVLGVVLA
TQHFGNPLTA VPCAVSSVCH SILGSVLAGI WRRSAPKQLE D
