BASS3_ARATH
ID BASS3_ARATH Reviewed; 431 AA.
AC Q8RXE8; Q8LCD3; Q9LSV9;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Probable sodium/metabolite cotransporter BASS3, chloroplastic;
DE AltName: Full=Bile acid transporter 3;
DE AltName: Full=Bile acid-sodium symporter family protein 3;
DE Flags: Precursor;
GN Name=BASS3; Synonyms=BAT3; OrderedLocusNames=At3g25410; ORFNames=MWL2.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=19542295; DOI=10.1105/tpc.109.066399;
RA Gigolashvili T., Yatusevich R., Rollwitz I., Humphry M., Gershenzon J.,
RA Fluegge U.-I.;
RT "The plastidic bile acid transporter 5 is required for the biosynthesis of
RT methionine-derived glucosinolates in Arabidopsis thaliana.";
RL Plant Cell 21:1813-1829(2009).
CC -!- FUNCTION: May function as sodium-coupled metabolite transporter across
CC the chloroplast envelope. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305|PubMed:19542295}; Multi-
CC pass membrane protein {ECO:0000305|PubMed:19542295}. Plastid,
CC chloroplast envelope {ECO:0000305|PubMed:19542295}.
CC -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC 2.A.28) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB01312.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB025639; BAB01312.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77008.1; -; Genomic_DNA.
DR EMBL; AY081301; AAL91190.1; -; mRNA.
DR EMBL; AY128781; AAM91181.1; -; mRNA.
DR EMBL; AY086664; AAM63721.1; -; mRNA.
DR RefSeq; NP_566764.1; NM_113437.3.
DR AlphaFoldDB; Q8RXE8; -.
DR SMR; Q8RXE8; -.
DR STRING; 3702.AT3G25410.1; -.
DR iPTMnet; Q8RXE8; -.
DR PaxDb; Q8RXE8; -.
DR PRIDE; Q8RXE8; -.
DR ProteomicsDB; 240642; -.
DR EnsemblPlants; AT3G25410.1; AT3G25410.1; AT3G25410.
DR GeneID; 822125; -.
DR Gramene; AT3G25410.1; AT3G25410.1; AT3G25410.
DR KEGG; ath:AT3G25410; -.
DR Araport; AT3G25410; -.
DR TAIR; locus:2094483; AT3G25410.
DR eggNOG; KOG2718; Eukaryota.
DR HOGENOM; CLU_034788_3_0_1; -.
DR InParanoid; Q8RXE8; -.
DR OMA; NIMMETT; -.
DR OrthoDB; 1148347at2759; -.
DR PhylomeDB; Q8RXE8; -.
DR PRO; PR:Q8RXE8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8RXE8; baseline and differential.
DR Genevisible; Q8RXE8; AT.
DR GO; GO:0009941; C:chloroplast envelope; IDA:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR004710; Bilac:Na_transpt.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR10361; PTHR10361; 1.
DR Pfam; PF01758; SBF; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..70
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 71..431
FT /note="Probable sodium/metabolite cotransporter BASS3,
FT chloroplastic"
FT /id="PRO_0000418604"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 387..407
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 104
FT /note="K -> R (in Ref. 4; AAM63721)"
FT /evidence="ECO:0000305"
FT CONFLICT 425
FT /note="T -> R (in Ref. 4; AAM63721)"
FT /evidence="ECO:0000305"
FT CONFLICT 429
FT /note="A -> T (in Ref. 4; AAM63721)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 431 AA; 45560 MW; 5B08D7BC22974500 CRC64;
MTLIASLSLP PPAIQRQSLS EFHNLPAKSQ SFNCQFRSSS SPLSSLHSSS LSNFLDFRLR
RRNSGLVPVV ACSTTPFMGR VGLHWRDGNM SLLSFCGGTD VTEKADSSQF WSALLPFVVA
LTAVAALSYP PSFTWVSKDL YAPALGGIML SIGIQLSVDD FALAFKRPVP LSVGFVAQYV
LKPLLGVLVA NAFGMPRTFY AGFILTCCVA GAQLSSYASS LSKADVAMSI LLTSSTTIAS
VIFTPLLSGL LIGSVVPVDA VAMSKSILQV VLVPITLGLV LNTYAKPVVT LLQPVMPFVA
MVCTSLCIGS PLSINRSQIL SAEGLGLIVP IVTFHAVAFA LGYWFSKIPG LRQEEEVSRT
ISLCTGMQSS TLAGLLASQF LGSSQAVPAA CSVVVMAIMG LCLASFWGNG FRIRDVLSLS
TPQSTGYTAE S
