ID   RS8_BOVIN               Reviewed;         208 AA.
AC   Q5E958; A1A4S0;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=40S ribosomal protein S8;
GN   Name=RPS8;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lymphoid epithelium;
RA   Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT   "Analysis of sequences obtained from constructed full-length bovine cDNA
RT   libraries.";
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus, and Hereford; TISSUE=Liver, and Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Identified in a IGF2BP1-dependent mRNP granule complex
CC       containing untranslated mRNAs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane
CC       {ECO:0000250|UniProtKB:P62241}; Lipid-anchor
CC       {ECO:0000250|UniProtKB:P62241}. Note=Localized in cytoplasmic mRNP
CC       granules containing untranslated mRNAs. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS8 family.
CC       {ECO:0000305}.
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DR   EMBL; BT021062; AAX09079.1; -; mRNA.
DR   EMBL; AY911334; AAW82102.1; -; mRNA.
DR   EMBL; BC102608; AAI02609.1; -; mRNA.
DR   EMBL; BC126849; AAI26850.1; -; mRNA.
DR   RefSeq; NP_001020488.1; NM_001025317.1.
DR   AlphaFoldDB; Q5E958; -.
DR   SMR; Q5E958; -.
DR   STRING; 9913.ENSBTAP00000020326; -.
DR   PaxDb; Q5E958; -.
DR   PeptideAtlas; Q5E958; -.
DR   PRIDE; Q5E958; -.
DR   Ensembl; ENSBTAT00000020326; ENSBTAP00000020326; ENSBTAG00000015285.
DR   GeneID; 404140; -.
DR   KEGG; bta:404140; -.
DR   CTD; 6202; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015285; -.
DR   VGNC; VGNC:34151; RPS8.
DR   eggNOG; KOG3283; Eukaryota.
DR   GeneTree; ENSGT00390000012433; -.
DR   HOGENOM; CLU_080597_1_1_1; -.
DR   InParanoid; Q5E958; -.
DR   OMA; VGRCDGY; -.
DR   OrthoDB; 1278610at2759; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000015285; Expressed in myometrium and 104 other tissues.
DR   ExpressionAtlas; Q5E958; baseline.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:1990904; C:ribonucleoprotein complex; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 1.10.168.20; -; 1.
DR   InterPro; IPR042563; Ribosomal_protein_S8e_euk.
DR   InterPro; IPR001047; Ribosomal_S8e.
DR   InterPro; IPR022309; Ribosomal_S8e/biogenesis_NSA2.
DR   InterPro; IPR018283; Ribosomal_S8e_CS.
DR   PANTHER; PTHR10394; PTHR10394; 1.
DR   Pfam; PF01201; Ribosomal_S8e; 1.
DR   TIGRFAMs; TIGR00307; eS8; 1.
DR   PROSITE; PS01193; RIBOSOMAL_S8E; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cytoplasm; Isopeptide bond; Lipoprotein; Membrane; Myristate;
KW   Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Ubl conjugation.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P62241"
FT   CHAIN           2..208
FT                   /note="40S ribosomal protein S8"
FT                   /id="PRO_0000231005"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..26
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         37
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P62242"
FT   MOD_RES         128
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P62242"
FT   MOD_RES         130
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P62241"
FT   MOD_RES         160
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P62241"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000250|UniProtKB:P62241"
FT   CROSSLNK        170
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:P62241"
FT   CROSSLNK        193
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:P62241"
SQ   SEQUENCE   208 AA;  24205 MW;  407FDF59171F7422 CRC64;
     MGISRDNWHK RRKTGGKRKP YHKKRKYELG RPAANTKIGP RRIHTVRVRG GNKKYRALRL
     DVGNFSWGSE CCTRKTRIID VVYNASNNEL VRTKTLVKNC IVLIDSTPYR QWYESHYALP
     LGRKKGAKLT PEEEEILNKK RSKKIQKKYD ERKKNAKISS LLEEQFQQGK LLACIASRPG
     QCGRADGYVL EGKELEFYLR KIKARKGK