ID   RS8_DICDI               Reviewed;         211 AA.
AC   Q54E24;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=40S ribosomal protein S8;
GN   Name=rps8; ORFNames=DDB_G0291864;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   PROTEIN SEQUENCE OF 82-96; 159-176 AND 196-202, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=AX2;
RA   Bienvenut W.V., Ura S., Insall R.H.;
RL   Submitted (JUL-2009) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS8 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000186; EAL61462.1; -; Genomic_DNA.
DR   RefSeq; XP_629872.1; XM_629870.1.
DR   AlphaFoldDB; Q54E24; -.
DR   SMR; Q54E24; -.
DR   STRING; 44689.DDB0230025; -.
DR   PaxDb; Q54E24; -.
DR   EnsemblProtists; EAL61462; EAL61462; DDB_G0291864.
DR   GeneID; 8628370; -.
DR   KEGG; ddi:DDB_G0291864; -.
DR   dictyBase; DDB_G0291864; rps8.
DR   eggNOG; KOG3283; Eukaryota.
DR   HOGENOM; CLU_080597_1_1_1; -.
DR   InParanoid; Q54E24; -.
DR   OMA; VGRCDGY; -.
DR   PhylomeDB; Q54E24; -.
DR   Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DDI-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DDI-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-DDI-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q54E24; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0031012; C:extracellular matrix; HDA:dictyBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:dictyBase.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 1.10.168.20; -; 1.
DR   InterPro; IPR042563; Ribosomal_protein_S8e_euk.
DR   InterPro; IPR001047; Ribosomal_S8e.
DR   InterPro; IPR022309; Ribosomal_S8e/biogenesis_NSA2.
DR   PANTHER; PTHR10394; PTHR10394; 1.
DR   Pfam; PF01201; Ribosomal_S8e; 1.
DR   TIGRFAMs; TIGR00307; eS8; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..211
FT                   /note="40S ribosomal protein S8"
FT                   /id="PRO_0000319986"
SQ   SEQUENCE   211 AA;  23890 MW;  4B3DACE25B2449C2 CRC64;
     MGISRDALHK HRLTGAARKC NYKKRKYELG RQAAKTKICS QGEEKRVRSI RVRGGHQKFR
     ALRLDTGNFS WATEKITRKC RILNVVYNAT SNDLVRTNTL VKGSIVQIDA TPYKQWYETH
     YGVVVGKKKS AKKDGEAEQV VKKSASLLAK LASRAKGRVL DSAIESQIGE GRFFARITSR
     PGQVGKCDGY ILEAKELEFY QRRLQKKKSA K