ID   RS8_LEIMA               Reviewed;         220 AA.
AC   P25204; Q4QAC2;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=40S ribosomal protein S8;
GN   Name=RPS8A; Synonyms=RPS8; ORFNames=LmjF24.2070, LmjF_24_2070;
GN   and
GN   Name=RPS8B; Synonyms=RPS8; ORFNames=LmjF24.2080, LmjF_24_2080;
OS   Leishmania major.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX   NCBI_TaxID=5664;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (RPS8A AND RPS8B).
RC   STRAIN=MHOM/IR/83/Lt252;
RX   PubMed=1741265; DOI=10.1093/nar/20.2.369;
RA   Bard E., Janeczko R.;
RT   "Sequence and genomic locus of a Leishmania protein homologous to rat
RT   ribosomal protein S8.";
RL   Nucleic Acids Res. 20:369-369(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (RPS8A AND RPS8B).
RC   STRAIN=MHOM/IL/81/Friedlin;
RX   PubMed=16020728; DOI=10.1126/science.1112680;
RA   Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA   Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA   Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA   Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA   Ciarloni L., Clayton C., Coulson R.M.R., Cronin A., Cruz A.K., Davies R.M.,
RA   De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA   Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA   Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA   Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA   Masuy D., Matthews K., Michaeli S., Mottram J.C., Mueller-Auer S.,
RA   Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA   Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA   Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA   Rutter S., Saunders D., Schaefer M., Schein J., Schwartz D.C., Seeger K.,
RA   Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA   Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA   Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA   Barrell B.G., Myler P.J.;
RT   "The genome of the kinetoplastid parasite, Leishmania major.";
RL   Science 309:436-442(2005).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS8 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X62942; CAA44714.1; -; Genomic_DNA.
DR   EMBL; X62942; CAA44715.1; -; Genomic_DNA.
DR   EMBL; FR796420; CAJ05344.1; -; Genomic_DNA.
DR   EMBL; FR796420; CAJ05346.1; -; Genomic_DNA.
DR   PIR; S20063; S20064.
DR   RefSeq; XP_001683725.1; XM_001683673.1.
DR   RefSeq; XP_001683726.1; XM_001683674.1.
DR   AlphaFoldDB; P25204; -.
DR   SMR; P25204; -.
DR   STRING; 5664.LmjF.24.2070; -.
DR   EnsemblProtists; CAJ05344; CAJ05344; LMJF_24_2070.
DR   EnsemblProtists; CAJ05346; CAJ05346; LMJF_24_2080.
DR   GeneID; 5652381; -.
DR   GeneID; 5652382; -.
DR   KEGG; lma:LMJF_24_2070; -.
DR   KEGG; lma:LMJF_24_2080; -.
DR   VEuPathDB; TriTrypDB:LmjF.24.2070; -.
DR   VEuPathDB; TriTrypDB:LMJLV39_240028500; -.
DR   VEuPathDB; TriTrypDB:LMJSD75_240027900; -.
DR   eggNOG; KOG3283; Eukaryota.
DR   InParanoid; P25204; -.
DR   OMA; VGRCDGY; -.
DR   Proteomes; UP000000542; Chromosome 24.
DR   GO; GO:0005737; C:cytoplasm; ISO:GeneDB.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; ISO:GeneDB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 1.10.168.20; -; 1.
DR   InterPro; IPR042563; Ribosomal_protein_S8e_euk.
DR   InterPro; IPR001047; Ribosomal_S8e.
DR   InterPro; IPR022309; Ribosomal_S8e/biogenesis_NSA2.
DR   InterPro; IPR018283; Ribosomal_S8e_CS.
DR   PANTHER; PTHR10394; PTHR10394; 1.
DR   Pfam; PF01201; Ribosomal_S8e; 1.
DR   TIGRFAMs; TIGR00307; eS8; 1.
DR   PROSITE; PS01193; RIBOSOMAL_S8E; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..220
FT                   /note="40S ribosomal protein S8"
FT                   /id="PRO_0000122247"
SQ   SEQUENCE   220 AA;  24922 MW;  5DD21FE14849445E CRC64;
     MGIVRSRLHK RKITGGKTKI HRKRMKAELG RLPANTRLGA RRVSPVRARG GNFKIRALRL
     DTGNFAWASE AIAHRVRLLD VVYNATSNEL VRTKTLVKNC IVAVDAAPFK RWYAKHYGID
     LDADKKSTKA AVAAEKKGRK SAHAAADKYD VNKASPKLQR EWTRRRRNHR VEKAIADQLR
     EGRVLARITS RPGQSGRADG ILLEGAELQF YLKRLEKKKK