ID   BBD1_ORYSI              Reviewed;         331 AA.
AC   B8A8D2;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Bifunctional nuclease 1;
DE            EC=3.1.-.-;
GN   Name=BBD1; ORFNames=OsI_03413;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Bifunctional nuclease with both RNase and DNase activities.
CC       Involved in basal defense response. Participates in abscisic acid-
CC       derived callose deposition following infection by a necrotrophic
CC       pathogen (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bifunctional nuclease family. {ECO:0000305}.
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DR   EMBL; CM000126; EEC71344.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8A8D2; -.
DR   SMR; B8A8D2; -.
DR   STRING; 39946.B8A8D2; -.
DR   EnsemblPlants; BGIOSGA000953-TA; BGIOSGA000953-PA; BGIOSGA000953.
DR   Gramene; BGIOSGA000953-TA; BGIOSGA000953-PA; BGIOSGA000953.
DR   HOGENOM; CLU_050306_1_0_1; -.
DR   OMA; QHSTSFW; -.
DR   Proteomes; UP000007015; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.690.10; -; 1.
DR   InterPro; IPR036104; BFN_sf.
DR   InterPro; IPR003729; Bi_nuclease_dom.
DR   Pfam; PF02577; DUF151; 1.
DR   SUPFAM; SSF103256; SSF103256; 1.
DR   PROSITE; PS51658; BFN; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nuclease; Nucleus; Reference proteome.
FT   CHAIN           1..331
FT                   /note="Bifunctional nuclease 1"
FT                   /id="PRO_0000419551"
FT   DOMAIN          126..261
FT                   /note="BFN"
FT   DOMAIN          291..326
FT                   /note="UVR"
SQ   SEQUENCE   331 AA;  37467 MW;  C75643FE7FEB4A92 CRC64;
     MEIINGPVLP RYAAPATGAL TSDAKISGQL LRRVHLRRRA CGLQGDHYRA ARRFFGFPSE
     RHARSGWVWP VCCSYGSSSD GDGAAAADYD ASGEEFVNSS VMEAVELRSV SDGFVIKMRD
     GKNLRCVQNN PRVLRLRDSA PHHAIVLKME DGSDLLLPII VMETPSIMLL AALRNIRIPR
     PTIYNVVKEM TERMGYAVRL VRITEMVHDA YYSRLYLAKI GNEEETISLD LKPSDAINIA
     FRCKVPIQVN RRIAYNNGLK VVQPTPSESY VSSDQFQCTR LDRPDDQPCF EAQEFDLVRN
     MLVAAVEERY KDAAQYRDQL FMFRAKKKNM I