BBD2_ORYSJ
ID BBD2_ORYSJ Reviewed; 325 AA.
AC Q6YZM6; A0A0N7KPQ6; A3BSC4; Q0J677;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Bifunctional nuclease 2;
DE Short=OsBBD2;
DE EC=3.1.-.-;
GN Name=BBD2; OrderedLocusNames=Os08g0357000, LOC_Os08g26870;
GN ORFNames=OsJ_27034, P0426E02.15;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Wuyujing 3;
RA Lu L.M., Qin M.L., Lan H.H., Wang P., Niu X.Q., Wu Z.J., Xie L.H.;
RT "Construction and characterization of a yeast two-hybrid cDNA library from
RT rice seedling leaves.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP IDENTIFICATION.
RX PubMed=20018603; DOI=10.1104/pp.109.147645;
RA You M.K., Shin H.Y., Kim Y.J., Ok S.H., Cho S.K., Jeung J.U., Yoo S.D.,
RA Kim J.K., Shin J.S.;
RT "Novel bifunctional nucleases, OmBBD and AtBBD1, are involved in abscisic
RT acid-mediated callose deposition in Arabidopsis.";
RL Plant Physiol. 152:1015-1029(2010).
CC -!- FUNCTION: Bifunctional nuclease with both RNase and DNase activities.
CC Involved in basal defense response. Participates in abscisic acid-
CC derived callose deposition following infection by a necrotrophic
CC pathogen (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the bifunctional nuclease family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF23538.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAZ42463.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; EU325988; ABY52937.1; -; mRNA.
DR EMBL; AP005520; BAD03757.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF23538.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014964; BAT05082.1; -; Genomic_DNA.
DR EMBL; CM000145; EAZ42463.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK105899; BAG97425.1; -; mRNA.
DR RefSeq; XP_015650236.1; XM_015794750.1.
DR AlphaFoldDB; Q6YZM6; -.
DR SMR; Q6YZM6; -.
DR STRING; 4530.OS08T0357000-02; -.
DR PaxDb; Q6YZM6; -.
DR PRIDE; Q6YZM6; -.
DR EnsemblPlants; Os08t0357000-02; Os08t0357000-02; Os08g0357000.
DR GeneID; 4345362; -.
DR Gramene; Os08t0357000-02; Os08t0357000-02; Os08g0357000.
DR KEGG; osa:4345362; -.
DR eggNOG; ENOG502QQ9S; Eukaryota.
DR HOGENOM; CLU_050306_1_0_1; -.
DR InParanoid; Q6YZM6; -.
DR OMA; NFATVCG; -.
DR OrthoDB; 966528at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR ExpressionAtlas; Q6YZM6; baseline and differential.
DR Genevisible; Q6YZM6; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0030891; C:VCB complex; IBA:GO_Central.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR Gene3D; 3.10.690.10; -; 1.
DR InterPro; IPR036104; BFN_sf.
DR InterPro; IPR003729; Bi_nuclease_dom.
DR Pfam; PF02577; DUF151; 1.
DR SUPFAM; SSF103256; SSF103256; 1.
DR PROSITE; PS51658; BFN; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Nuclease; Nucleus; Reference proteome.
FT CHAIN 1..325
FT /note="Bifunctional nuclease 2"
FT /id="PRO_0000419552"
FT DOMAIN 119..254
FT /note="BFN"
FT DOMAIN 285..320
FT /note="UVR"
SQ SEQUENCE 325 AA; 36038 MW; 0AD341C31921367D CRC64;
MAMEGPILCR AVMQAKLPVT MISNSLTKSG QLGTAFLGCV CKYRNITRLI SPIYQPAQKN
FATVCGSFSS SSDGNGYMAG NFSESDEDYV NSTVLEAVEV RSGAEGYVIK MRDGKNLRCV
HNNSQGRNIP ESAPQPAIVL RIEDGSETLL PIIVLEMPSV LLMAAIRNVH IARPTIYQVV
KEMIDKMGYE VKLVRINKRI QEAYCAELFL TKVGDHTESI TFDLRPSDAI NIAVRCKVPI
QVHRSLAYSD GIRSVEPARM AIAAGMSDGL LFTELDRPDG QPCVEAQEFG LIRNMLIAAV
EERYKDAATW RDKLMLLRSK RKNWA