ID   RS8_THETH               Reviewed;         138 AA.
AC   P24319; P74907;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 2.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=30S ribosomal protein S8;
GN   Name=rpsH; Synonyms=rps8;
OS   Thermus thermophilus.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX   NCBI_TaxID=274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=VK1;
RX   PubMed=7519982; DOI=10.1111/j.1432-1033.1994.tb19011.x;
RA   Vysotskaya V.S., Tischenko S., Garber M.B., Kern D., Ehresmann C.,
RA   Ehresmann B.;
RT   "The ribosomal protein S8 from Thermus thermophilus VK1. Sequencing of the
RT   gene, overexpression of the protein in Escherichia coli and interaction
RT   with rRNA.";
RL   Eur. J. Biochem. 223:437-445(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 38-138.
RC   STRAIN=VK1;
RX   PubMed=9249063; DOI=10.1016/s0378-1119(97)00072-3;
RA   Vysotskaya V.S., Shcherbakov D.V., Garber M.B.;
RT   "Sequencing and analysis of the Thermus thermophilus ribosomal protein gene
RT   cluster equivalent to the spectinomycin operon.";
RL   Gene 193:23-30(1997).
RN   [3]
RP   X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
RC   STRAIN=VK1;
RX   PubMed=9636713; DOI=10.1006/jmbi.1998.1758;
RA   Nevskaya N., Tishchenko S., Nikulin A., Al-Karadaghi S., Liljas A.,
RA   Ehresmann B., Ehresmann C., Garber M.B., Nikonov S.;
RT   "Crystal structure of ribosomal protein S8 from Thermus thermophilus
RT   reveals a high degree of structural conservation of a specific RNA binding
RT   site.";
RL   J. Mol. Biol. 279:233-244(1998).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       to 16S rRNA central domain where it helps coordinate assembly of the
CC       platform of the 30S subunit. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S5 and
CC       S12 (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS8 family.
CC       {ECO:0000305}.
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DR   EMBL; X79551; CAA56094.1; -; Genomic_DNA.
DR   EMBL; X90765; CAA62287.1; -; Genomic_DNA.
DR   PIR; S15441; S15441.
DR   RefSeq; WP_011173705.1; NZ_LR027517.1.
DR   PDB; 1AN7; X-ray; 2.90 A; A/B=3-138.
DR   PDB; 4V8X; X-ray; 3.35 A; AH/CH=1-138.
DR   PDBsum; 1AN7; -.
DR   PDBsum; 4V8X; -.
DR   AlphaFoldDB; P24319; -.
DR   SMR; P24319; -.
DR   GeneID; 3169811; -.
DR   OMA; FDQGYIL; -.
DR   EvolutionaryTrace; P24319; -.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01302_B; Ribosomal_S8_B; 1.
DR   InterPro; IPR000630; Ribosomal_S8.
DR   InterPro; IPR035987; Ribosomal_S8_sf.
DR   PANTHER; PTHR11758; PTHR11758; 1.
DR   Pfam; PF00410; Ribosomal_S8; 1.
DR   SUPFAM; SSF56047; SSF56047; 1.
DR   PROSITE; PS00053; RIBOSOMAL_S8; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..138
FT                   /note="30S ribosomal protein S8"
FT                   /id="PRO_0000126512"
FT   CONFLICT        64
FT                   /note="K -> N (in Ref. 2; CAA62287)"
FT                   /evidence="ECO:0000305"
FT   HELIX           5..17
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   TURN            18..20
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          22..27
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   HELIX           30..41
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          44..53
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          56..63
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          65..68
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          70..72
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          75..79
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          83..85
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   HELIX           97..99
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   HELIX           103..106
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          108..114
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          117..120
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   HELIX           121..127
FT                   /evidence="ECO:0007829|PDB:1AN7"
FT   STRAND          131..137
FT                   /evidence="ECO:0007829|PDB:1AN7"
SQ   SEQUENCE   138 AA;  15838 MW;  49CC858AD1E4DB5A CRC64;
     MLTDPIADML TRIRNATRVY KESTDVPASR FKEEILRILA REGFIKGYER VDVDGKPYLR
     VYLKYGPRRQ GPDPRPEQVI HHIRRISKPG RRVYVGVKEI PRVRRGLGIA ILSTSKGVLT
     DREARKLGVG GELICEVW