BBP1_ASHGO
ID BBP1_ASHGO Reviewed; 353 AA.
AC Q755J5;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Spindle pole component BBP1;
GN Name=BBP1; OrderedLocusNames=AFL172W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Component of the spindle pole body (SPB) required for
CC insertion of the nascent SPB into the nuclear envelope and for the
CC proper execution of spindle pole body (SPB) duplication. Connects the
CC central plaque of the SPB with the half-bridge. Required for proper
CC localization of CDC5 at the SPB and for proper M-phase progression (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, spindle pole body {ECO:0000250}. Note=Associates with the
CC periphary of the central plaque. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BBP1 family. {ECO:0000305}.
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DR EMBL; AE016819; AAS53202.2; -; Genomic_DNA.
DR RefSeq; NP_985378.2; NM_210732.2.
DR AlphaFoldDB; Q755J5; -.
DR STRING; 33169.AAS53202; -.
DR PRIDE; Q755J5; -.
DR EnsemblFungi; AAS53202; AAS53202; AGOS_AFL172W.
DR GeneID; 4621603; -.
DR KEGG; ago:AGOS_AFL172W; -.
DR eggNOG; ENOG502RYZ2; Eukaryota.
DR HOGENOM; CLU_711875_0_0_1; -.
DR InParanoid; Q755J5; -.
DR OMA; AQDDTNY; -.
DR Proteomes; UP000000591; Chromosome VI.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR InterPro; IPR029330; Bbp1_C.
DR InterPro; IPR029328; Bbp1_N.
DR Pfam; PF15272; BBP1_C; 1.
DR Pfam; PF15271; BBP1_N; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..353
FT /note="Spindle pole component BBP1"
FT /id="PRO_0000409170"
FT REGION 27..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 187..318
FT /evidence="ECO:0000255"
FT COMPBIAS 27..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 353 AA; 39459 MW; 752CE20C91A88793 CRC64;
MGWLGDNSED STGAVRWVMD ALLGKRESPS QKYRREFAQD DTNNRLQVPR SAGARRRRTG
SLDSEFRARY ELLPDETEGA GASLLSPVDL RPAGTAARES GTPGRAGWAG GAAGTLGGGD
GGCDGGRDGD TFGRARGSED VAFRPPRADN PLVSALFAQP SSPDAGLPGS FPGRAPRARD
PTHDYLALLD QLARNNRDLH SLQQDLEARE ERDRRETSYR DRYLQLRQEL IQELKQSKTM
YDNYTALYER YKALKDAEHP DYAELVSKLE AQIVDLTIAD QQKDRRHQEE LLRLQLQYEA
RIHELERKLN HQNSTYTAND TATPASTVDS GSISPYHKYN DTIDTQFLNH IVK