ID   BBP1_KLULA              Reviewed;         398 AA.
AC   Q6CL13;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Spindle pole component BBP1;
GN   Name=BBP1; OrderedLocusNames=KLLA0F06534g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the spindle pole body (SPB) required for
CC       insertion of the nascent SPB into the nuclear envelope and for the
CC       proper execution of spindle pole body (SPB) duplication. Connects the
CC       central plaque of the SPB with the half-bridge. Required for proper
CC       localization of CDC5 at the SPB and for proper M-phase progression (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, spindle pole body {ECO:0000250}. Note=Associates with the
CC       periphary of the central plaque. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BBP1 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG98084.1; -; Genomic_DNA.
DR   RefSeq; XP_455376.1; XM_455376.1.
DR   AlphaFoldDB; Q6CL13; -.
DR   SMR; Q6CL13; -.
DR   STRING; 28985.XP_455376.1; -.
DR   EnsemblFungi; CAG98084; CAG98084; KLLA0_F06534g.
DR   GeneID; 2895038; -.
DR   KEGG; kla:KLLA0_F06534g; -.
DR   eggNOG; ENOG502RYZ2; Eukaryota.
DR   HOGENOM; CLU_711875_0_0_1; -.
DR   InParanoid; Q6CL13; -.
DR   OMA; AQDDTNY; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029330; Bbp1_C.
DR   InterPro; IPR029328; Bbp1_N.
DR   Pfam; PF15272; BBP1_C; 1.
DR   Pfam; PF15271; BBP1_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..398
FT                   /note="Spindle pole component BBP1"
FT                   /id="PRO_0000409172"
FT   REGION          93..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          351..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          201..350
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        356..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   398 AA;  46517 MW;  D811CAD2A9CDEFF5 CRC64;
     MGSDDTGGLF KWTIDALFNR DTSPSTMYDK QLQQDSFDEE IYSRPRASSF SDPDIYSKYE
     LLRDEDEPDL LRPVSMNGLP YEKQDTNTFH ARRARERRVQ ETPNIRRAPN PNDPIISKLF
     QVDEDDSQLN TNEMRSQREK FNTGRLPGKF PSPTKQYNAR ISNRDAFTGA ERKAASTAPA
     IPPVAPSVQN LDYTPEYVKL MDKLSLNNKE LRDLKVDVRE RQKHGMEKET ELKKKYLQIR
     QELIQELKQS KMIYDNYCKL YYKYKGVKRS IQLPTQTLAS NSSMLDKIAS LEKQIVDLSI
     EKDRLKKKSE ERILSVELQK KELENKFEVE RMIYERRIKD LEEKLYVHEH PIRPATDTSP
     VSSSSFMPHT QETSDSTASP YKEYNNTIDT QFLRNLVK