ID   BBP1_LACTC              Reviewed;         376 AA.
AC   C5DBV2;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Spindle pole component BBP1;
GN   Name=BBP1; OrderedLocusNames=KLTH0A05588g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Component of the spindle pole body (SPB) required for
CC       insertion of the nascent SPB into the nuclear envelope and for the
CC       proper execution of spindle pole body (SPB) duplication. Connects the
CC       central plaque of the SPB with the half-bridge. Required for proper
CC       localization of CDC5 at the SPB and for proper M-phase progression (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, spindle pole body {ECO:0000250}. Note=Associates with the
CC       periphary of the central plaque. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BBP1 family. {ECO:0000305}.
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DR   EMBL; CU928165; CAR21259.1; -; Genomic_DNA.
DR   RefSeq; XP_002551701.1; XM_002551655.1.
DR   AlphaFoldDB; C5DBV2; -.
DR   STRING; 559295.C5DBV2; -.
DR   PRIDE; C5DBV2; -.
DR   EnsemblFungi; CAR21259; CAR21259; KLTH0A05588g.
DR   GeneID; 8290505; -.
DR   KEGG; lth:KLTH0A05588g; -.
DR   eggNOG; ENOG502RYZ2; Eukaryota.
DR   HOGENOM; CLU_711875_0_0_1; -.
DR   InParanoid; C5DBV2; -.
DR   OMA; AQDDTNY; -.
DR   OrthoDB; 1331565at2759; -.
DR   Proteomes; UP000002036; Chromosome A.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029330; Bbp1_C.
DR   InterPro; IPR029328; Bbp1_N.
DR   Pfam; PF15272; BBP1_C; 1.
DR   Pfam; PF15271; BBP1_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Spindle pole component BBP1"
FT                   /id="PRO_0000409173"
FT   REGION          34..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          103..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          204..350
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        34..58
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  44032 MW;  91B8A5F3CC399D93 CRC64;
     MIWNNDDTEH STGGLYRWTM DALFGRQISP SRKFKEVSQD DTNYNMKSHK DKQWDGHGFQ
     PRTRSSSASF DRSFLQRYEL LQDEEEQDIM RPVRSPARPY LSAGHAAGQD AALANDESTD
     TFSNKRQRFK GKFSGPKYHD ESLKFRAPAK NDPFISKLFQ RESPEHPSNL PGKFPSPFKQ
     ALGLPAGVQV QLDPEEQIPQ KMFTDEYLQL LAELDQNGQK LKQLQQGLHQ KQQDHILQET
     SYREKYHVMR QELITELKQS KKLYDNYYRL YEKHKKMRAL DTDASRLRQR ISDLEAQVVD
     ASIEKAEEVR KLNETIFQLE FREQETQSKH ERERIRYQSR IAELESIVES RLSISNGVQN
     PPLRERIKPV NSSARI