ID   BBR1_SCHCO              Reviewed;         541 AA.
AC   P78741;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2001, sequence version 2.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Pheromone B beta 1 receptor;
GN   Name=BBR1;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 44201 / CBS 340.81 / UVM 4-40 / 4-40;
RX   PubMed=9178005; DOI=10.1093/genetics/146.2.541;
RA   Vaillancourt L.J., Raudaskoski M., Specht C.A., Raper C.A.;
RT   "Multiple genes encoding pheromones and a pheromone receptor define the B
RT   beta 1 mating-type specificity in Schizophyllum commune.";
RL   Genetics 146:541-551(1997).
RN   [2]
RP   SEQUENCE REVISION.
RA   Raper C.A.;
RL   Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Receptor for the BBP1 pheromone, a prenylated mating factor.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 4 family.
CC       {ECO:0000305}.
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DR   EMBL; U74495; AAB41858.2; -; Genomic_DNA.
DR   AlphaFoldDB; P78741; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004933; F:mating-type a-factor pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   InterPro; IPR001546; GPCR_Pheromne_A_rcpt.
DR   InterPro; IPR001499; GPCR_STE3.
DR   PANTHER; PTHR28097; PTHR28097; 1.
DR   Pfam; PF02076; STE3; 1.
DR   PRINTS; PR00899; GPCRSTE3.
DR   PRINTS; PR00900; PHEROMONEAR.
PE   3: Inferred from homology;
KW   G-protein coupled receptor; Membrane; Pheromone response; Receptor;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..541
FT                   /note="Pheromone B beta 1 receptor"
FT                   /id="PRO_0000195073"
FT   TOPO_DOM        1..3
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25..33
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        55..69
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        91..109
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        131..150
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        172..205
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        227..264
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        286..541
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          364..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          414..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..388
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        439..463
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..481
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  59587 MW;  1EABBE95D548A1AA CRC64;
     MHPEFAPVAF LSAASLALPL PWHWRAGNVA TLSIIAWLFI MNMIYGINAV IWAGSARITA
     VVYCDITTKL TIGGNFALPA ACLCLCIHLE RVASVRAAQT TAADKRRRTI FELAMCWLLP
     IIFMALHYVV QGHRFDIVED FGCRPATYYS IPAIFIVWVP PLTMAAASLV YASLAIRHFM
     HRRLSFAMHL QARSSALTTS RYLRLILMAI VQLVWLVVTT AYTLWFSSMT LNLRPWTTWA
     DVHSNFGRIQ TWPAIITPAV ILRGACTLWW MVPASTWIFV AFFAFGNDAV EEYKRVLNVV
     LSGARRALPE GFLSEKKRDL KGFSLPSFVK GSVPLGDSSS STRKDSLPDK AVLPVNRSVT
     MTTTTSTVVS SMPPPYSLPP PPPPQKYTSP LDSLDYSADA DRISISSSVD TSGYTIEILP
     ETPSTSSSTP PSPSSPQYPR SPSSQGSHVV DDYYYTSSPQ DSLPHDIPAP PSLPPPTHMP
     DEAHISPSHA VPSRPPAFPP YPFARDMRPA ASEPMSPRPI TYPSMSPTHR DIASVFPGGR
     R