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BBR_HORVU
ID   BBR_HORVU               Reviewed;         350 AA.
AC   Q8GUC3;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Protein Barley B recombinant;
DE            Short=Protein BBR;
GN   Name=BBR;
OS   Hordeum vulgare (Barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=4513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, DNA-BINDING, TISSUE
RP   SPECIFICITY, AND SUBCELLULAR LOCATION.
RX   PubMed=12795701; DOI=10.1046/j.1365-313x.2003.01767.x;
RA   Santi L., Wang Y., Stile M.R., Berendzen K.W., Wanke D., Roig C., Pozzi C.,
RA   Mueller K., Mueller J., Rohde W., Salamini F.;
RT   "The GA octodinucleotide repeat binding factor BBR participates in the
RT   transcriptional regulation of the homeobox gene Bkn3.";
RL   Plant J. 34:813-826(2003).
CC   -!- FUNCTION: Transcriptional regulator that specifically binds to GA-rich
CC       elements (GAGA-repeats) present in regulatory sequences of genes
CC       involved in developmental processes. Positively regulates the homeotic
CC       gene BKN3. {ECO:0000269|PubMed:12795701}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12795701}.
CC   -!- TISSUE SPECIFICITY: Ubiquitously expressed.
CC       {ECO:0000269|PubMed:12795701}.
CC   -!- SIMILARITY: Belongs to the BBR/BPC family. {ECO:0000305}.
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DR   EMBL; AJ507214; CAD45251.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8GUC3; -.
DR   SMR; Q8GUC3; -.
DR   EnsemblPlants; HORVU.MOREX.r2.4HG0327390.1; HORVU.MOREX.r2.4HG0327390.1.CDS.1; HORVU.MOREX.r2.4HG0327390.
DR   EnsemblPlants; HORVU.MOREX.r2.4HG0327390.1.mrna1; HORVU.MOREX.r2.4HG0327390.1.mrna1.cds1; HORVU.MOREX.r2.4HG0327390.1.
DR   Gramene; HORVU.MOREX.r2.4HG0327390.1; HORVU.MOREX.r2.4HG0327390.1.CDS.1; HORVU.MOREX.r2.4HG0327390.
DR   Gramene; HORVU.MOREX.r2.4HG0327390.1.mrna1; HORVU.MOREX.r2.4HG0327390.1.mrna1.cds1; HORVU.MOREX.r2.4HG0327390.1.
DR   ExpressionAtlas; Q8GUC3; baseline.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   InterPro; IPR010409; GAGA-bd_tscrpt_act.
DR   PANTHER; PTHR31421; PTHR31421; 1.
DR   Pfam; PF06217; GAGA_bind; 1.
DR   SMART; SM01226; GAGA_bind; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..350
FT                   /note="Protein Barley B recombinant"
FT                   /id="PRO_0000413442"
FT   REGION          43..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          93..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           199..219
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        98..118
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        215..232
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   350 AA;  38978 MW;  668DF5294A12E061 CRC64;
     MDDDGSLSIR NWGFYETMKG NLGLQLMPSV TGGHRDTKPL LPNGTFLQHH TPPHHPPHSH
     HPRDYGNGEP SGGMPAEPPA IHMDFVRNEA WMHPSQHQHQ HQHQHQHQHQ HQHQLQHQHQ
     HQHSRELKVL NAVPVGPAPH IGHPGHAVHH HPTGFGMMPD ARGAHTLQMM QPQEPPVPDE
     EKITPPLVED HSVVGSKPPV KKRQQGRQPK VPKPKKPKKD ATPGEDGAPK ARAPRSRGPL
     KPVEMVINGI DFDISRIPTP VCSCTGAPQQ CYRWGAGGWQ SACCTTSIST YPLPMNTKRR
     GARIAGRKMS QGAFKKVLEK LAGEGYNLNN PIDLKTFWAK HGTNKFVTIR
 
 
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