BBR_HORVU
ID BBR_HORVU Reviewed; 350 AA.
AC Q8GUC3;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Protein Barley B recombinant;
DE Short=Protein BBR;
GN Name=BBR;
OS Hordeum vulgare (Barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=4513;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, DNA-BINDING, TISSUE
RP SPECIFICITY, AND SUBCELLULAR LOCATION.
RX PubMed=12795701; DOI=10.1046/j.1365-313x.2003.01767.x;
RA Santi L., Wang Y., Stile M.R., Berendzen K.W., Wanke D., Roig C., Pozzi C.,
RA Mueller K., Mueller J., Rohde W., Salamini F.;
RT "The GA octodinucleotide repeat binding factor BBR participates in the
RT transcriptional regulation of the homeobox gene Bkn3.";
RL Plant J. 34:813-826(2003).
CC -!- FUNCTION: Transcriptional regulator that specifically binds to GA-rich
CC elements (GAGA-repeats) present in regulatory sequences of genes
CC involved in developmental processes. Positively regulates the homeotic
CC gene BKN3. {ECO:0000269|PubMed:12795701}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12795701}.
CC -!- TISSUE SPECIFICITY: Ubiquitously expressed.
CC {ECO:0000269|PubMed:12795701}.
CC -!- SIMILARITY: Belongs to the BBR/BPC family. {ECO:0000305}.
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DR EMBL; AJ507214; CAD45251.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8GUC3; -.
DR SMR; Q8GUC3; -.
DR EnsemblPlants; HORVU.MOREX.r2.4HG0327390.1; HORVU.MOREX.r2.4HG0327390.1.CDS.1; HORVU.MOREX.r2.4HG0327390.
DR EnsemblPlants; HORVU.MOREX.r2.4HG0327390.1.mrna1; HORVU.MOREX.r2.4HG0327390.1.mrna1.cds1; HORVU.MOREX.r2.4HG0327390.1.
DR Gramene; HORVU.MOREX.r2.4HG0327390.1; HORVU.MOREX.r2.4HG0327390.1.CDS.1; HORVU.MOREX.r2.4HG0327390.
DR Gramene; HORVU.MOREX.r2.4HG0327390.1.mrna1; HORVU.MOREX.r2.4HG0327390.1.mrna1.cds1; HORVU.MOREX.r2.4HG0327390.1.
DR ExpressionAtlas; Q8GUC3; baseline.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR InterPro; IPR010409; GAGA-bd_tscrpt_act.
DR PANTHER; PTHR31421; PTHR31421; 1.
DR Pfam; PF06217; GAGA_bind; 1.
DR SMART; SM01226; GAGA_bind; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Transcription; Transcription regulation.
FT CHAIN 1..350
FT /note="Protein Barley B recombinant"
FT /id="PRO_0000413442"
FT REGION 43..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 199..219
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 98..118
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 38978 MW; 668DF5294A12E061 CRC64;
MDDDGSLSIR NWGFYETMKG NLGLQLMPSV TGGHRDTKPL LPNGTFLQHH TPPHHPPHSH
HPRDYGNGEP SGGMPAEPPA IHMDFVRNEA WMHPSQHQHQ HQHQHQHQHQ HQHQLQHQHQ
HQHSRELKVL NAVPVGPAPH IGHPGHAVHH HPTGFGMMPD ARGAHTLQMM QPQEPPVPDE
EKITPPLVED HSVVGSKPPV KKRQQGRQPK VPKPKKPKKD ATPGEDGAPK ARAPRSRGPL
KPVEMVINGI DFDISRIPTP VCSCTGAPQQ CYRWGAGGWQ SACCTTSIST YPLPMNTKRR
GARIAGRKMS QGAFKKVLEK LAGEGYNLNN PIDLKTFWAK HGTNKFVTIR