ID   RSA3_KLULA              Reviewed;         203 AA.
AC   Q6CK62;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Ribosome assembly protein 3;
GN   Name=RSA3; OrderedLocusNames=KLLA0F13266g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for efficient biogenesis of the 60S ribosomal
CC       subunit. {ECO:0000250}.
CC   -!- SUBUNIT: Associates with nucleolar pre-ribosomal particles.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RSA3 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG98385.1; -; Genomic_DNA.
DR   RefSeq; XP_455677.1; XM_455677.1.
DR   AlphaFoldDB; Q6CK62; -.
DR   STRING; 28985.XP_455677.1; -.
DR   EnsemblFungi; CAG98385; CAG98385; KLLA0_F13266g.
DR   GeneID; 2895970; -.
DR   KEGG; kla:KLLA0_F13266g; -.
DR   eggNOG; ENOG502S5DP; Eukaryota.
DR   HOGENOM; CLU_119118_0_0_1; -.
DR   InParanoid; Q6CK62; -.
DR   OMA; DAHNNNK; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:EnsemblFungi.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:EnsemblFungi.
DR   InterPro; IPR028217; Rsa3_C.
DR   Pfam; PF14615; Rsa3; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis.
FT   CHAIN           1..203
FT                   /note="Ribosome assembly protein 3"
FT                   /id="PRO_0000097465"
FT   REGION          1..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..90
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   203 AA;  22392 MW;  AEDD3B498C8D2B8E CRC64;
     MSEGHIAAIS KTNKRKNRRK KRRTQDVSDS SSDSSSDSEN SSVEDNDTKL ETVEKAASDV
     EDVTLSDIDM DKEEDEAALD DKKASRKEGS VLSSETVDKL NKVGLTTSDL TGNNGIHLGN
     IDLNKMSATL DESSNKLLEN NKDKNGLKNQ YLSMLFESYG DDMNELRNAP DFTSKTLVML
     ANVLKDGGDM FDLETLKTIV EDK