ID   RSD_SALHS               Reviewed;         162 AA.
AC   B4TCT4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN   Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181}; OrderedLocusNames=SeHA_C4496;
OS   Salmonella heidelberg (strain SL476).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=454169;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL476;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC       transcription activation by preventing the interaction between the
CC       primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC       and with promoter DNA. May be involved in replacement of the RNA
CC       polymerase sigma subunit from RpoD to RpoS during the transition from
CC       exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC       Rule:MF_01181}.
CC   -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC   -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01181}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001120; ACF66127.1; -; Genomic_DNA.
DR   RefSeq; WP_000934315.1; NC_011083.1.
DR   AlphaFoldDB; B4TCT4; -.
DR   SMR; B4TCT4; -.
DR   KEGG; seh:SeHA_C4496; -.
DR   HOGENOM; CLU_142729_0_0_6; -.
DR   OMA; DVIDHWL; -.
DR   Proteomes; UP000001866; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.20.120.1370; -; 1.
DR   HAMAP; MF_01181; Rsd; 1.
DR   InterPro; IPR038309; Rsd/AlgQ_sf.
DR   InterPro; IPR023785; Sigma70_reg_Rsd.
DR   InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR   Pfam; PF04353; Rsd_AlgQ; 1.
DR   PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Transcription; Transcription regulation.
FT   CHAIN           1..162
FT                   /note="Regulator of sigma D"
FT                   /id="PRO_1000138201"
SQ   SEQUENCE   162 AA;  18653 MW;  60A52C4D8B0142D8 CRC64;
     MLNQLENLTE RVGGSNKLVD RWLDVRKHLL VAYYNLVGIK PGKESYMRLN EKALDDFCQS
     LVDYLSAGHF SIYERILHKL EGNGQLLHAA KIWPLLEDNT QRIMDYYDTS LETAIDHDNC
     LEFQQALSDI GEALEARFVL EDKLIMLVFD AMHDGARVKR PA