RSD_SALNS
ID RSD_SALNS Reviewed; 162 AA.
AC B4T0Z7;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181};
GN OrderedLocusNames=SNSL254_A4498;
OS Salmonella newport (strain SL254).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=423368;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SL254;
RX PubMed=21602358; DOI=10.1128/jb.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC transcription activation by preventing the interaction between the
CC primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC and with promoter DNA. May be involved in replacement of the RNA
CC polymerase sigma subunit from RpoD to RpoS during the transition from
CC exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
CC -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
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DR EMBL; CP001113; ACF62583.1; -; Genomic_DNA.
DR RefSeq; WP_000934315.1; NZ_CCMR01000001.1.
DR AlphaFoldDB; B4T0Z7; -.
DR SMR; B4T0Z7; -.
DR EnsemblBacteria; ACF62583; ACF62583; SNSL254_A4498.
DR KEGG; see:SNSL254_A4498; -.
DR HOGENOM; CLU_142729_0_0_6; -.
DR OMA; DVIDHWL; -.
DR Proteomes; UP000008824; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.20.120.1370; -; 1.
DR HAMAP; MF_01181; Rsd; 1.
DR InterPro; IPR038309; Rsd/AlgQ_sf.
DR InterPro; IPR023785; Sigma70_reg_Rsd.
DR InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR Pfam; PF04353; Rsd_AlgQ; 1.
DR PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transcription; Transcription regulation.
FT CHAIN 1..162
FT /note="Regulator of sigma D"
FT /id="PRO_1000138202"
SQ SEQUENCE 162 AA; 18653 MW; 60A52C4D8B0142D8 CRC64;
MLNQLENLTE RVGGSNKLVD RWLDVRKHLL VAYYNLVGIK PGKESYMRLN EKALDDFCQS
LVDYLSAGHF SIYERILHKL EGNGQLLHAA KIWPLLEDNT QRIMDYYDTS LETAIDHDNC
LEFQQALSDI GEALEARFVL EDKLIMLVFD AMHDGARVKR PA