RSD_SALTI
ID RSD_SALTI Reviewed; 162 AA.
AC Q8Z327; Q7C6P6;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181};
GN OrderedLocusNames=STY3720, t3466;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC transcription activation by preventing the interaction between the
CC primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC and with promoter DNA. May be involved in replacement of the RNA
CC polymerase sigma subunit from RpoD to RpoS during the transition from
CC exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
CC -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
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DR EMBL; AL513382; CAD09479.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO70982.1; -; Genomic_DNA.
DR RefSeq; NP_457909.1; NC_003198.1.
DR RefSeq; WP_000934311.1; NZ_WSUR01000043.1.
DR AlphaFoldDB; Q8Z327; -.
DR SMR; Q8Z327; -.
DR STRING; 220341.16504596; -.
DR EnsemblBacteria; AAO70982; AAO70982; t3466.
DR KEGG; stt:t3466; -.
DR KEGG; sty:STY3720; -.
DR PATRIC; fig|220341.7.peg.3792; -.
DR eggNOG; COG3160; Bacteria.
DR HOGENOM; CLU_142729_0_0_6; -.
DR OMA; DVIDHWL; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.20.120.1370; -; 1.
DR HAMAP; MF_01181; Rsd; 1.
DR InterPro; IPR038309; Rsd/AlgQ_sf.
DR InterPro; IPR023785; Sigma70_reg_Rsd.
DR InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR Pfam; PF04353; Rsd_AlgQ; 1.
DR PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transcription; Transcription regulation.
FT CHAIN 1..162
FT /note="Regulator of sigma D"
FT /id="PRO_0000268886"
SQ SEQUENCE 162 AA; 18683 MW; A2CFCFB82A8842C0 CRC64;
MLNQLENLME RVGGSNKLVD RWLDVRKHLL VAYYNLVGIK PGKESYMRLN EKALDDFCQS
LVDYLSAGHF SIYERILHKL EGNGQLLHAA KIWPLLEDNT QRIMDYYDTS LETAIDHDNC
LEFQQALSDI GEALEARFVL EDKLIMLVFD AMHDGARVKR PA
