ID   RSD_SHIDS               Reviewed;         158 AA.
AC   Q32AG8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN   Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181}; OrderedLocusNames=SDY_3731;
OS   Shigella dysenteriae serotype 1 (strain Sd197).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300267;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sd197;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA   Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA   Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA   Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT   bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC       transcription activation by preventing the interaction between the
CC       primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC       and with promoter DNA. May be involved in replacement of the RNA
CC       polymerase sigma subunit from RpoD to RpoS during the transition from
CC       exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC       Rule:MF_01181}.
CC   -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC   -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01181}.
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DR   EMBL; CP000034; ABB63687.1; -; Genomic_DNA.
DR   RefSeq; WP_000934296.1; NC_007606.1.
DR   RefSeq; YP_405178.1; NC_007606.1.
DR   AlphaFoldDB; Q32AG8; -.
DR   SMR; Q32AG8; -.
DR   STRING; 300267.SDY_3731; -.
DR   EnsemblBacteria; ABB63687; ABB63687; SDY_3731.
DR   KEGG; sdy:SDY_3731; -.
DR   PATRIC; fig|300267.13.peg.4423; -.
DR   HOGENOM; CLU_142729_0_0_6; -.
DR   OMA; DVIDHWL; -.
DR   Proteomes; UP000002716; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.20.120.1370; -; 1.
DR   HAMAP; MF_01181; Rsd; 1.
DR   InterPro; IPR038309; Rsd/AlgQ_sf.
DR   InterPro; IPR023785; Sigma70_reg_Rsd.
DR   InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR   Pfam; PF04353; Rsd_AlgQ; 1.
DR   PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..158
FT                   /note="Regulator of sigma D"
FT                   /id="PRO_0000268888"
SQ   SEQUENCE   158 AA;  18231 MW;  CDA7E9CBD515EC08 CRC64;
     MLNQLDNLTE RVRGSNKLVD RWLHVRKHLL VAYYNLGGIK PGKESYMRLN EKALDDFCQS
     LVDYLSAGHF SIYERILHKL ESNGQLARAA KIWPQLEANT QQIMDYYDSS LETAIDHDNY
     LEFQQVLSDI GEALEARFVL EDKLILLVLD AARVKHPA