RSD_SHISS
ID RSD_SHISS Reviewed; 158 AA.
AC Q3YUY9;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181}; OrderedLocusNames=SSON_4168;
OS Shigella sonnei (strain Ss046).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300269;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ss046;
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC transcription activation by preventing the interaction between the
CC primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC and with promoter DNA. May be involved in replacement of the RNA
CC polymerase sigma subunit from RpoD to RpoS during the transition from
CC exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
CC -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
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DR EMBL; CP000038; AAZ90673.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3YUY9; -.
DR SMR; Q3YUY9; -.
DR EnsemblBacteria; AAZ90673; AAZ90673; SSON_4168.
DR KEGG; ssn:SSON_4168; -.
DR HOGENOM; CLU_142729_0_0_6; -.
DR OMA; DVIDHWL; -.
DR Proteomes; UP000002529; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.20.120.1370; -; 1.
DR HAMAP; MF_01181; Rsd; 1.
DR InterPro; IPR038309; Rsd/AlgQ_sf.
DR InterPro; IPR023785; Sigma70_reg_Rsd.
DR InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR Pfam; PF04353; Rsd_AlgQ; 1.
DR PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transcription; Transcription regulation.
FT CHAIN 1..158
FT /note="Regulator of sigma D"
FT /id="PRO_0000268889"
SQ SEQUENCE 158 AA; 18243 MW; BDB699DAC440A808 CRC64;
MLNQLDNLTE RVRGSNKLVD RWLHVRKHLL VAYYNLVGIK PGKESYMRLN EKALDDFCQS
LVDYLSAGHF SIYERILHKL EGNGQLARAA KIWPQLEANT QQIMDYYDSS LETAIDHDNY
LEFQQVLSDI GEALEARFVL EDKLILLVLD AARVKHPA