ID   RSD_YERPA               Reviewed;         169 AA.
AC   Q1C1V0;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN   Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181}; OrderedLocusNames=YPA_3610;
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC       transcription activation by preventing the interaction between the
CC       primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC       and with promoter DNA. May be involved in replacement of the RNA
CC       polymerase sigma subunit from RpoD to RpoS during the transition from
CC       exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC       Rule:MF_01181}.
CC   -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC   -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01181}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABG15572.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000308; ABG15572.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_002210683.1; NZ_CP009906.1.
DR   AlphaFoldDB; Q1C1V0; -.
DR   SMR; Q1C1V0; -.
DR   EnsemblBacteria; ABG15572; ABG15572; YPA_3610.
DR   GeneID; 57974980; -.
DR   KEGG; ypa:YPA_3610; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.20.120.1370; -; 1.
DR   HAMAP; MF_01181; Rsd; 1.
DR   InterPro; IPR038309; Rsd/AlgQ_sf.
DR   InterPro; IPR023785; Sigma70_reg_Rsd.
DR   InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR   Pfam; PF04353; Rsd_AlgQ; 1.
DR   PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Transcription; Transcription regulation.
FT   CHAIN           1..169
FT                   /note="Regulator of sigma D"
FT                   /id="PRO_0000268892"
SQ   SEQUENCE   169 AA;  19187 MW;  C9DE048201317252 CRC64;
     MLNRLESLTQ RVGGSNELID QWLHARKELL VSYCTVIGIK PQKEKHTPLN AKTLENFCHN
     LVDYLSSGHF HLYDRIIKEV EGASSPKMAL TAKIHPALKN NTQTIMAFHD CYTNIEIDDD
     SCTEYQQALS DIGEALDARF RLEDQLIQWA AESWQAAQLA DADKKSQVN