RSD_YERPG
ID RSD_YERPG Reviewed; 169 AA.
AC A9R8D2;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Regulator of sigma D {ECO:0000255|HAMAP-Rule:MF_01181};
GN Name=rsd {ECO:0000255|HAMAP-Rule:MF_01181};
GN OrderedLocusNames=YpAngola_A0456;
OS Yersinia pestis bv. Antiqua (strain Angola).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=349746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Angola;
RX PubMed=20061468; DOI=10.1128/jb.01518-09;
RA Eppinger M., Worsham P.L., Nikolich M.P., Riley D.R., Sebastian Y., Mou S.,
RA Achtman M., Lindler L.E., Ravel J.;
RT "Genome sequence of the deep-rooted Yersinia pestis strain Angola reveals
RT new insights into the evolution and pangenome of the plague bacterium.";
RL J. Bacteriol. 192:1685-1699(2010).
CC -!- FUNCTION: Binds RpoD and negatively regulates RpoD-mediated
CC transcription activation by preventing the interaction between the
CC primary sigma factor RpoD with the catalytic core of the RNA polymerase
CC and with promoter DNA. May be involved in replacement of the RNA
CC polymerase sigma subunit from RpoD to RpoS during the transition from
CC exponential growth to the stationary phase. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
CC -!- SUBUNIT: Interacts with RpoD. {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01181}.
CC -!- SIMILARITY: Belongs to the Rsd/AlgQ family. {ECO:0000255|HAMAP-
CC Rule:MF_01181}.
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DR EMBL; CP000901; ABX86078.1; -; Genomic_DNA.
DR RefSeq; WP_002210683.1; NZ_CP009935.1.
DR AlphaFoldDB; A9R8D2; -.
DR SMR; A9R8D2; -.
DR GeneID; 57974980; -.
DR KEGG; ypg:YpAngola_A0456; -.
DR PATRIC; fig|349746.12.peg.1412; -.
DR OMA; DVIDHWL; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 1.20.120.1370; -; 1.
DR HAMAP; MF_01181; Rsd; 1.
DR InterPro; IPR038309; Rsd/AlgQ_sf.
DR InterPro; IPR023785; Sigma70_reg_Rsd.
DR InterPro; IPR007448; Sigma70_reg_Rsd_AlgQ.
DR Pfam; PF04353; Rsd_AlgQ; 1.
DR PIRSF; PIRSF016548; Rsd_AlgQ; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transcription; Transcription regulation.
FT CHAIN 1..169
FT /note="Regulator of sigma D"
FT /id="PRO_1000138207"
SQ SEQUENCE 169 AA; 19187 MW; C9DE048201317252 CRC64;
MLNRLESLTQ RVGGSNELID QWLHARKELL VSYCTVIGIK PQKEKHTPLN AKTLENFCHN
LVDYLSSGHF HLYDRIIKEV EGASSPKMAL TAKIHPALKN NTQTIMAFHD CYTNIEIDDD
SCTEYQQALS DIGEALDARF RLEDQLIQWA AESWQAAQLA DADKKSQVN