ID   RSE1_CANAL              Reviewed;        1219 AA.
AC   Q5A7S5; A0A1D8PJ07;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Pre-mRNA-splicing factor RSE1;
GN   Name=RSE1; Synonyms=SAP130; OrderedLocusNames=CAALFM_C300660WA;
GN   ORFNames=CaO19.12846, CaO19.5391;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RSE1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017625; AOW28116.1; -; Genomic_DNA.
DR   RefSeq; XP_717766.1; XM_712673.1.
DR   AlphaFoldDB; Q5A7S5; -.
DR   SMR; Q5A7S5; -.
DR   STRING; 237561.Q5A7S5; -.
DR   GeneID; 3640538; -.
DR   KEGG; cal:CAALFM_C300660WA; -.
DR   CGD; CAL0000182953; orf19.12846.
DR   VEuPathDB; FungiDB:C3_00660W_A; -.
DR   eggNOG; KOG1898; Eukaryota.
DR   HOGENOM; CLU_003246_0_1_1; -.
DR   InParanoid; Q5A7S5; -.
DR   OMA; FFLVQTE; -.
DR   OrthoDB; 97116at2759; -.
DR   PRO; PR:Q5A7S5; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..1219
FT                   /note="Pre-mRNA-splicing factor RSE1"
FT                   /id="PRO_0000218627"
SQ   SEQUENCE   1219 AA;  136352 MW;  C5E5CC30495E1C46 CRC64;
     MMMRDGNISG PKKKKFTTKC RPFSFYKNRH IIMLINDESV YLYNLTLKPP SYYISSIVGQ
     FYKQDNSTKN AQQLVLVSST TLQLFEINEE AGKLELQSSQ NLLGIINSIE KICLSEVDGV
     VITSDSGNLS ILQYDNKTKK FISKIQEPMT KNGWGRNYVG ENLAIDPENR CILVAAMEKN
     KLFYKIESNS SGSKELSSPL EAHSKQVLCL KIVALNTDHN NPLFGALELT PEKKCIINYY
     ELDQGLNHVV KKKPNSSNSD PLPNDVNYLI PLPGHIGGMV VCGTNWCFYD KLDGPRIYLP
     LPRRNGQTQD SIIVNHVTHV LKKKKFFILL QNALGDLFKL TVDYDFDKEI IKNISITYFD
     TIPPALSLNI FKNGFLFANV LNNDKLLYQF EKLGDDLTEG ELVINSSDYE SLNSVRESVT
     SFKLKGLDNL ALIDVLETLS PITDSKIIDS KLVTLSSHSY VKSITHGVPT TTLVESPLPI
     TPTDIFTTKL SLESANDEYL VISSSLSSKT LVLSIGEVVE DVEDSEFVLD QPTIAVQQVG
     IASVVQIYSN GIKHVRTVNG NKKTTDWFPP AGITITHATT NNQQVLIALS NLSVVYFEID
     ATDDQLIEYQ DRLEIATTIT AMAIQENISE KSPFAIIGCS DETIQVVSLQ EHNCLEIKSL
     QALSANSSSL KMLKSSGKET HVHIGMENGV YARIKIDTIN GNLSNSRVKY IGSKPVSLSV
     IKFSNEIEGI LAISSAPWIS YLYRDSFKIT PLLEIDITNG SSFISEDIGG EGIVGIKDNN
     LIIFSVGKED SVFDPSQDLT IATTKLRYTP RKMITNGNRL FISESEYNVQ GPFKCNINGD
     VKENVDEDYY EAFGYEWKQN SWASCIQVVD SKSNQVIQSL QLDGNESIVS MSAVSFNKTS
     TPSVPASHLV VGVCTNQTIL PNSYDKSYLY TFKIGKKHLQ LVHKTELDHI PQVLENFQDK
     LLVASGNHIR LYDIGQKQLL KKSTTIIDFS TNINKIIPQT NRIIICDSHK SSIVFAKFDE
     SQNQFVPFAD DVMKRQITSI MNLDIDTLIG GDKFGNIFVT RIDEDISKQA DDDWTILKTQ
     DGILNSCPYK LQNLIEFHIG DIITSFNLGC LNLAGTESVI YTGLQGTIGL LIPLVSKSEV
     ELLFNLQLYM QQSQNNLVGK DHLKLRSYYN PIKNVIDGDL LERFLEFDIS LKIEISRKLN
     KSVNDIEKKL IDLRNRSAF