ID   RSE1_NEUCR              Reviewed;        1209 AA.
AC   Q7RYR4; U9W538;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Pre-mRNA-splicing factor rse1;
DE   AltName: Full=mRNA-splicing protein 5;
GN   Name=msp-5; Synonyms=rse1; ORFNames=NCU00396;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RSE1 family. {ECO:0000305}.
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DR   EMBL; CM002238; ESA43359.1; -; Genomic_DNA.
DR   RefSeq; XP_011393827.1; XM_011395525.1.
DR   AlphaFoldDB; Q7RYR4; -.
DR   SMR; Q7RYR4; -.
DR   STRING; 5141.EFNCRP00000000235; -.
DR   EnsemblFungi; ESA43359; ESA43359; NCU00396.
DR   GeneID; 3873404; -.
DR   KEGG; ncr:NCU00396; -.
DR   VEuPathDB; FungiDB:NCU00396; -.
DR   HOGENOM; CLU_003246_0_0_1; -.
DR   InParanoid; Q7RYR4; -.
DR   Proteomes; UP000001805; Chromosome 3, Linkage Group III.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..1209
FT                   /note="Pre-mRNA-splicing factor rse1"
FT                   /id="PRO_0000218634"
SQ   SEQUENCE   1209 AA;  134039 MW;  AEAC42E71DCD610D CRC64;
     MATTSNMFLY SLTIQPPTAV TQALLGQFSG TKEQQILTAS GSRLTLLQPD PRQGKVNTLL
     SHDIFGIVRA IASFRLAGSH KDYIILATDS GRITIIEYLP KTNKFQRIHL ETFGKSGVRR
     VIPGQYLAAD PKGRACLISA LEKNKLVYVL NRNSQAELTI SSPLEAHKPG VLVLSLVALD
     VGYANPVFAA LELDYTDADQ DPTGQAREEV ETQLVYYELD LGLNHVVRKW SDTVDRTSSL
     LFQVPGGNDG PSGVLVCGEE NVTYRHSNQE AFRVPIPRRS GATEDPQRKR VIVSGVMHKL
     KGSAGAFFFL LQTDDGDLFK VTIDMIEDSD GNPTGEVKRL KIKYFDTIPV ATSLCILKSG
     FLFAASEFGN HHFYQFEKLG DDDEELEFSS DDFPTDPTAS YNPVYFHPRP LENLVLVESI
     DSMNPQVDCK VANLTGEDAP QIYSVCGNGA RSTFRMLKHG LEVSEIVASE LPGTPSAVWT
     TKLTKYDQYD AYIVLSFTNG TLVLSIGETV EEVSDSGFLT TAPTLAVQQM GEDGLIQVHP
     KGIRHIVQGR VNEWPAPQHR SIVAATANEN QVVIALSSGE IVYFEMDSDG SLAEYDEKKE
     MSGTVTSLSV GQVPEGLKRS SFLAVGCDDC TVRILSLDPD STLEMKSIQA LTAAPSALSI
     MSMEDSFGGS TLYLHIGLHS GVYLRTVLDE VTGELTDTRQ KFLGPKPTRL FQVSVQDQPC
     VLALSSRPWL GYTDPLTKGF MMTPLSYTEL EYGWNFSSEQ CLEGMVGIHA NYLRIFSIEK
     LGDNMIQKSI PLTYTPKHLV KHPEQPYFYT IESDNNTLPP ELRAKLLEQQ SNGDATVLPP
     EDFGYPRAKG RWASCISIID PISEEPRVLQ RIDLDNNEAA VSAAIVPFAS QEGESFLVVG
     TGKDMVLDPR QFTEGYIHVY RFHEDGRDLE FIHKTRVEEP PLALIPFQGR LLAGVGKTLR
     IYDLGLKQLL RKAQADVTPT LIVSLQSQGN RIIVGDLQQG ITYVVYKAEG NRLIPFADDT
     LNRWTTCTTM VDYESVAGGD KFGNIYIVRC PERVSQETDE PGSEIHLMHA RNYLHGTPNR
     LSLQVHFYTQ DLPTSICKTS LVVGGQDVLL WSGLQGTVGV FIPFVSREDV DFFQNLENHM
     RAEDPPLAGR DHLIYRGYYT PVKGVIDGDL CERFSLLPND KKQMIAGELD RSVREIERKI
     SDIRTRSAF